SCHEMBL19809100

SCHEMBL19809100

COC[C@@H]1CN(C(=O)O)C[C@H](C(=O)N(C2CC2)C(C)c2nn(CCCNC(=O)OC)c3nc(C)ccc23)O1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17005474 1.00 REN (0.67) REN
SCHEMBL17013626 0.92 REN (0.63) REN
SCHEMBL17013628 0.89 REN (0.78) REN
SCHEMBL17012898 0.86 REN (0.55) REN
SCHEMBL17005438 0.85 REN (0.70) REN
SCHEMBL19809098 0.85 REN (0.70) REN
SCHEMBL17005392 0.84 REN (0.66) REN
SCHEMBL17013112 0.83 REN (0.75) REN
SCHEMBL17013647 0.83 REN (0.81) REN
SCHEMBL17013658 0.83 REN (0.81) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2933248-B1 NOVEL RENIN INHIBITOR MITSUBISHI TANABE PHARMA CORP (JP) 2018-01-31 — — EP disclosed
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