SCHEMBL198100

SCHEMBL198100

CN(C)c1cc(-c2ccccn2)nc(-c2ccccn2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.58
CCR5 P51681 3/20 0.58
CCR8 P51685 3/20 0.58
KDM4E B2RXH2 7/20 0.57
LMNA P02545 4/20 0.57
SMN1; SMN2 Q16637 4/20 0.57
HTT P42858 3/20 0.57
L3MBTL1 Q9Y468 3/20 0.57
TP53 P04637 3/20 0.57
ALOX15 P16050 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
ALPL P05186 1/20 0.57
HSP90AA1 P07900 1/20 0.57
ALPI P09923 1/20 0.57
ALPG P10696 1/20 0.57
MAPK1 P28482 1/20 0.57
HIF1A Q16665 2/20 0.54
CYP1A2 P05177 1/20 0.54
POLB P06746 1/20 0.54
METAP1 P53582 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7570543 0.85 CCR1 (0.55) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL30636788 0.85 KDM4E (0.54) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL7966923 0.85 KDM4E (0.54) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL12907125 0.84 KDM4E (0.51) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL30950139 0.83 KDM4E (0.44) CCR1CCR5CCR8KDM4ELMNA
Terpyridine SCHEMBL7551889 0.80 KDM4E (0.62) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL14802108 0.80 SLC2A1 (0.49) CCR1CCR5CCR8KDM4ELMNA
Dipyridyl SCHEMBL28393736 0.79 KDM4E (0.78) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL2542175 0.79 CCR1 (0.47) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL1104803 0.78 CCR1 (0.64) CCR1CCR5CCR8KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9891185-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2018-02-13 US disclosed
US-9662057-B2 Integrated sample acquisition and analyte measurement method ABBOTT DIABETES CARE INC. (US) 2017-05-30 US disclosed
US-20160334356-A1 Small Volume In Vitro Analyte Sensor THERASENSE, INC. 2016-11-17 US disclosed
US-20160235350-A1 Integrated Sample Acquisition and Analyte Measurement Device THERASENSE, INC. 2016-08-18 US disclosed
US-9341591-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-05-17 US disclosed
US-9316609-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-04-19 US disclosed
US-9291592-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-03-22 US disclosed
US-9271669-B2 Method for integrated sample acquisition and analyte measurement device ABBOTT DIABETES CARE INC. (US) 2016-03-01 US disclosed
US-9234863-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-01-12 US disclosed
US-20150245791-A1 Integrated Sample Acquisition and Analyte Measurement Device THERASENSE, INC. 2015-09-03 US disclosed
US-20040060818-A1 Small volume in vitro analyte sensor and methods of making THERASENSE, INC. (US) 2004-04-01 US disclosed
EP-1119637-B1 SMALL VOLUME IN VITRO ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR THERASENSE INC (US) 2004-03-24 EP disclosed
US-20040054267-A1 Small volume in vitro analyte sensor THERASENSE, INC. 2004-03-18 US disclosed
US-20030199744-A1 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator THERASENSE, INC. (US) 2003-10-23 US disclosed
US-6618934-B1 Method of manufacturing small volume in vitro analyte sensor THERASENSE, INC. 2003-09-16 US disclosed
US-6592745-B1 Analytical sensors for the detection of bioanalytes in a small volume sample; to monitor glucose in diabetic patients and lactate during critical care THERASENSE, INC. 2003-07-15 US disclosed
US-6591125-B1 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator THERASENSE, INC. 2003-07-08 US disclosed
US-6461496-B1 BLOOD GLUCOSE THERASENSE, INC. 2002-10-08 US disclosed
US-6338790-B1 DETECTION OF BIOANALYTES IN A SMALL VOLUME SAMPLE; CONCENTRATION OF A BIOMOLECULE, SUCH AS GLUCOSE OR LACTATE, USING TECHNIQUES SUCH AS COULOMETRY, AMPEROMETRY, AND POTENTIOMETRY. AN ENZYME CAPABLE OF CATALYZING THE THERASENSE, INC. 2002-01-15 US disclosed
US-6299757-B1 ANALYTICAL SENSORS FOR THE DETECTION OF BIOANALYTES; ESPECIALLY MONITORING GLUCOSE LEVELS IN DIABETIC PATIENTS THERASENSE, INC. 2001-10-09 US disclosed