Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CCR1 | P32246 | 3/20 | 0.54 |
| ▸ | CCR5 | P51681 | 3/20 | 0.54 |
| ▸ | CCR8 | P51685 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | METAP1 | P53582 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.54 |
| ▸ | KDM6B | O15054 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | KDM5C | P41229 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.47 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30636788 | 1.00 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL196641 | 0.88 | ALDH1A1 (0.53) | KDM4ECCR1CCR5CCR8ABL1 | |
| SCHEMBL198100 | 0.85 | CCR1 (0.58) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL30345721 | 0.81 | ASIC3 (0.53) | KDM4ECYP1A2ABL1BCRTP53 | |
| SCHEMBL1716712 | 0.81 | ASIC3 (0.53) | KDM4ECYP1A2ABL1BCRTP53 | |
| Dipyridyl SCHEMBL28393736 | 0.79 | KDM4E (0.78) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL3177903 | 0.78 | DCTPP1 (0.55) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL29978861 | 0.78 | DCTPP1 (0.55) | KDM4ELMNACCR1CCR5CCR8 | |
| Terpyridine SCHEMBL7551889 | 0.77 | KDM4E (0.62) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL13360717 | 0.77 | CYP1A2 (0.57) | KDM4ELMNACYP1A2HIF1AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024354-B | Preparation method of Rui Mi Buti Ni | 天津凯莱英制药有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-117024354-A | Preparation method of Rui Mi Buti Ni | 天津凯莱英制药有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-113999083-A | Novel method for synthesizing 2, 2-difluoroethyl aromatic compound | 山东理工大学 | 2022-02-01 | — | — | CN | claimed |
| CN-108530343-B | Rhein specific group modified organic compound, aryl metal complex thereof, preparation method and application thereof | 南京师范大学 | 2021-07-27 | — | — | CN | claimed |
| CN-117024354-B | Preparation method of Rui Mi Buti Ni | 天津凯莱英制药有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-117024354-A | Preparation method of Rui Mi Buti Ni | 天津凯莱英制药有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-113683557-B | Application of cyclopentadienyl iridium/rhodium dimer | 南京师范大学 | 2023-07-14 | — | — | CN | disclosed |
| CN-113683557-A | Application of cyclopentadienyl iridium/rhodium dimer | 南京师范大学 | 2021-11-23 | — | — | CN | disclosed |
| CN-108530343-B | Rhein specific group modified organic compound, aryl metal complex thereof, preparation method and application thereof | 南京师范大学 | 2021-07-27 | — | — | CN | disclosed |
| US-6187928-B1 | TREATING FUNGAL DISEASES | THE ROCKEFELLER UNIVERSITY | 2001-02-13 | — | — | US | disclosed |
| US-6087510-A | Method of use of imidazolium cations | THE ROCKEFELLER UNIVERSITY (US) | 2000-07-11 | — | — | US | disclosed |
| US-5969150-A | FLUORESCENT COMPOUNDS FOR MEDICAL DIAGNOSIS, DRUGS AND LABELS OR FUNGICIDES AND VIRICIDES | THE ROCKEFELLER UNIVERSITY (US) | 1999-10-19 | — | — | US | disclosed |
| US-5874587-A | FLUORESCENCE | THE ROCKEFELLER UNIVERSITY (US) | 1999-02-23 | — | — | US | disclosed |