⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16008544 | 0.67 | — | — | |
| SCHEMBL21849205 | 0.55 | — | — | |
| SCHEMBL22412870 | 0.52 | — | — | |
| SCHEMBL3217459 | 0.50 | — | — | |
| SCHEMBL27633682 | 0.46 | — | — | |
| SCHEMBL641884 | 0.46 | — | — | |
| SCHEMBL30043153 | 0.43 | — | — | |
| SCHEMBL7162800 | 0.41 | — | — | |
| SCHEMBL6439813 | 0.41 | — | — | |
| SCHEMBL8151672 | 0.38 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539256-B | Tricyclic compounds and medical uses thereof | 上海拓界生物医药科技有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116171280-A | Casein kinase 1 delta modulators | 詹森药业有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-114539256-A | Tricyclic compound and medical use thereof | 上海拓界生物医药科技有限公司 | 2022-05-27 | — | — | CN | disclosed |
| US-20180030003-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-02-01 | — | — | US | disclosed |