⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL863362 | 0.60 | — | — | |
| SCHEMBL14580381 | 0.57 | — | — | |
| SCHEMBL19810844 | 0.55 | — | — | |
| SCHEMBL21968884 | 0.48 | — | — | |
| Water SCHEMBL31307175 | 0.48 | — | — | |
| Water SCHEMBL2502262 | 0.35 | — | — | |
| Water SCHEMBL3628203 | 0.31 | — | — | |
| Water SCHEMBL349062 | 0.31 | — | — | |
| Water SCHEMBL28607990 | 0.31 | — | — | |
| Water SCHEMBL2502590 | 0.31 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242531-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-08-03 | — | — | US | disclosed |
| US-20200102311-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | US | disclosed |