⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11288832 | 1.00 | — | — | |
| SCHEMBL1259524 | 0.79 | KCNA5 (0.37) | — | |
| SCHEMBL5241067 | 0.78 | — | — | |
| SCHEMBL27569808 | 0.78 | — | — | |
| SCHEMBL1609019 | 0.77 | KCNA5 (0.37) | — | |
| SCHEMBL8648295 | 0.77 | — | — | |
| SCHEMBL13066097 | 0.77 | KCNA5 (0.37) | — | |
| SCHEMBL57306 | 0.77 | — | — | |
| SCHEMBL21954031 | 0.77 | HRH3 (0.38) | — | |
| Hydrochloric Acid SCHEMBL28186582 | 0.76 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1094 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116813523-A | Bisindole biphenyl compound and preparation method and application thereof | 贵州医科大学 | 2023-09-29 | — | — | CN | claimed |
| US-20230226062-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORPORATION | 2023-07-20 | — | — | US | claimed |
| CN-113874357-A | Metallobeta-lactamase inhibitors | 国家科学研究中心 | 2021-12-31 | — | — | CN | claimed |
| WO-2021188431-A1 | METHOD OF TREATING GLIOMA CANCER USING TARP GAMMA 8-DEPENDENT AMPA RECEPTOR ANTAGONISTS | ES THERAPEUTICS LLC (US) | 2021-09-23 | — | — | WO | claimed |
| EP-3880665-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES | Centre national de la recherche scientifique (FR) | 2021-09-22 | — | — | EP | claimed |
| EP-3148995-B1 | 6-SUBSTITUTED-3H-1,3-BENZOTHIAZOL-2-ONE COMPOUNDS AS TARP-GAMMA 8 DEPENDENT AMPA RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2020-09-23 | — | — | EP | claimed |
| US-10758542-B2 | Substituted pyrazolo[l,5-a]pyrimidine compounds as Trk kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2020-09-01 | — | — | US | claimed |
| CN-108314677-B | EZH2 inhibitor and application thereof | 安徽中科拓苒药物科学研究有限公司 | 2020-06-30 | — | — | CN | claimed |
| WO-2020099645-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-05-22 | — | — | WO | claimed |
| CN-107835813-B | 6, 7-dihydropyrido [2,1-a ] phthalazin-2-ones for the treatment and prevention of hepatitis b virus infections | 豪夫迈·罗氏有限公司 | 2020-04-24 | — | — | CN | claimed |
| EP-0623606-A2 | Peptidic ketones as interleukin-1beta-converting enzyme inhibitors | STERLING WINTHROP INC. (US) | 1994-11-09 | — | — | EP | claimed |
| EP-0564356-A1 | 4-phenylaminomethylimidazole derivatives, process for their preparation, angiotensin II receptor antagonists and their application in therapy | FOURNIER INDUSTRIE ET SANTE (FR) | 1993-10-06 | — | — | EP | claimed |
| EP-0410358-B1 | AROMATIC CARBOXYLIC ACID AMIDES, THEIR PREPARATION AND THEIR USE AS MEDICINES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-09-29 | — | — | EP | claimed |
| EP-0362695-B1 | PYRROLOCARBAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1991-04-03 | — | — | EP | claimed |
| US-4912107-A | Pyrrolocarbazole derivatives, compositions containing them, and methods for using them | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1990-03-27 | — | — | US | claimed |
| US-4558046-A | ANTIALLERGENS | FARMITALIA CARLO ERBA, S.P.A. (IT) | 1985-12-10 | — | — | US | claimed |
| EP-0144341-A4 | NOVEL 4,5-g(a)EPOXYMORPHINAN-6-SPIRO-2'-(4'-CARBOXY,1',3'-THIAZOLIDINE) DERIVATIVES. | KEY PHARMA (US) | 1985-07-30 | — | — | EP | claimed |
| EP-0144341-A1 | NOVEL 4,5-g(a)EPOXYMORPHINAN-6-SPIRO-2'-(4'-CARBOXY,1',3'-THIAZOLIDINE) DERIVATIVES. | KEY PHARMA (US) | 1985-06-19 | — | — | EP | claimed |
| WO-1984003627-A1 | NOVEL 4,5alphaEPOXYMORPHINAN-6-SPIRO-2'-(4'-CARBOXY,1',3'-THIAZOLIDINE) DERIVATIVES | KEY PHARMA (US) | 1984-09-27 | — | — | WO | claimed |
| US-3974275-A | 1,4-Dihydropyridine carboxylic acid esters useful as coronary vessel dilators and anti-hypertensives | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-10 | — | — | US | claimed |