Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PRCP | P42785 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | ULK1 | O75385 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3806378 | 1.00 | HDAC8 (0.46) | HDAC8HDAC6PRCPHTR2CHTR2B | |
| SCHEMBL29572383 | 1.00 | HDAC8 (0.46) | HDAC8HDAC6PRCPHTR2CHTR2B | |
| SCHEMBL7383341 | 0.98 | HDAC8 (0.50) | HDAC8HDAC6PRCPHTR2CHTR2B | |
| SCHEMBL443064 | 0.93 | — | — | |
| SCHEMBL6160852 | 0.93 | — | — | |
| SCHEMBL15962430 | 0.84 | PRCP (0.46) | PRCPHTR2CHTR2BULK1DPP7 | |
| SCHEMBL13306379 | 0.81 | PRCP (0.47) | PRCPHTR2CHTR2BULK1DPP7 | |
| SCHEMBL29288134 | 0.81 | PRCP (0.44) | PRCPHTR2CHTR2BULK1DPP7 | |
| SCHEMBL22221409 | 0.81 | PRCP (0.47) | PRCPHTR2CHTR2BULK1DPP7 | |
| SCHEMBL1965000 | 0.81 | PRCP (0.47) | PRCPHTR2CHTR2BULK1DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018021977-A1 | GLYCINE METABOLISM MODULATORS AND USES THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-02-01 | — | — | WO | disclosed |