Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.54 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.54 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.54 |
| ▸ | RRM1 | P23921 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CD40 | P25942 | 2/20 | 0.40 |
| ▸ | TLR2 | O60603 | 5/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 4/20 | 0.39 |
| ▸ | NMT2 | O60551 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19820018 | 1.00 | GNAI3 (0.54) | GNAI3GNAO1GNAI1RRM1DPP7 | |
| SCHEMBL16572280 | 0.92 | GNAI3 (0.59) | GNAI3GNAO1GNAI1RRM1DPP7 | |
| SCHEMBL16572290 | 0.92 | GNAI3 (0.59) | GNAI3GNAO1GNAI1RRM1DPP7 | |
| SCHEMBL16572077 | 0.91 | GNAI3 (0.57) | GNAI3GNAO1GNAI1RRM1DPP7 | |
| SCHEMBL19820108 | 0.89 | GNAI3 (0.41) | GNAI3GNAO1GNAI1RRM1DPP7 | |
| SCHEMBL19820040 | 0.89 | GNAI3 (0.41) | GNAI3GNAO1GNAI1RRM1DPP7 | |
| SCHEMBL16572301 | 0.85 | GNAI3 (0.51) | GNAI3GNAO1GNAI1RRM1DPP7 | |
| SCHEMBL20094956 | 0.85 | GNAI3 (0.40) | GNAI3GNAO1GNAI1RRM1DPP7 | |
| SCHEMBL16572332 | 0.83 | GNAI3 (0.49) | GNAI3GNAO1GNAI1RRM1DPP7 | |
| SCHEMBL16572353 | 0.83 | GNAI3 (0.49) | GNAI3GNAO1GNAI1RRM1DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180111907-A1 | DENDRIMER LIKE AMINO AMIDES POSSESSING SODIUM CHANNEL BLOCKER ACTIVITY FOR THE TREATMENT OF DRY EYE AND OTHER MUCOSAL DISEASES | PARION SCIENCES, INC. | 2018-04-26 | — | — | US | disclosed |
| US-9878988-B2 | Dendrimer like amino amides possessing sodium channel blocker activity for the treatment of dry eye and other mucosal diseases | PARION SCIENCES, INC. (US) | 2018-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180111907-A1 | DENDRIMER LIKE AMINO AMIDES POSSESSING SODIUM CHANNEL BLOCKER ACTIVITY FOR THE TREATMENT OF DRY EYE AND OTHER MUCOSAL DISEASES | SCNN1B, SCNN1A, SCNN1G | GNAI3 852/4885GNAO1 683/4885GNAI1 721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.