SCHEMBL19820186

SCHEMBL19820186

CC1(C)C(/C=C/C=C2/N(Cc3ccccc3)c3ccc(C(=O)O)cc3C2(C)C)=[N+](Cc2ccccc2)c2ccc(C(=O)O)cc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 11/20 0.56
MAPT P10636 3/20 0.44
LMNA P02545 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
NPC1 O15118 1/20 0.44
USP2 O75604 1/20 0.44
S1PR2 O95136 1/20 0.44
POLB P06746 1/20 0.44
ALPG P10696 1/20 0.44
THRB P10828 1/20 0.44
PKM P14618 1/20 0.44
XBP1 P17861 1/20 0.44
CRHBP P24387 1/20 0.44
HTT P42858 1/20 0.44
RECQL P46063 1/20 0.44
RAB9A P51151 1/20 0.44
BLM P54132 1/20 0.44
CRHR2 Q13324 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12602395 0.96 PRMT1 (0.53) PRMT1MAPTLMNAMEN1KMT2A
SCHEMBL5651412 0.84 PRMT1 (0.44) PRMT1MAPTLMNAMEN1KMT2A
SCHEMBL5651416 0.84 PRMT1 (0.44) PRMT1MAPTLMNAMEN1KMT2A
SCHEMBL14227705 0.78 PRMT1 (0.51) PRMT1MAPTLMNAMEN1KMT2A
SCHEMBL15762987 0.78 PRMT1 (0.61) PRMT1MAPTLMNAMEN1KMT2A
SCHEMBL18070559 0.78 PRMT1 (0.57) PRMT1MAPTLMNAMEN1KMT2A
SCHEMBL19063564 0.78 PTPN1 (0.67) PRMT1MAPTLMNAMEN1KMT2A
SCHEMBL14769834 0.77 FOLH1 (0.38) PRMT1MAPTLMNAMEN1KMT2A
SCHEMBL13070158 0.77 PRMT1 (0.44) PRMT1MAPTLMNAMEN1KMT2A
SCHEMBL5653734 0.77 ADORA1 (0.41) PRMT1MAPTLMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9881745-B2 Dye sensitized solar cell ADEKA CORPORATION (JP) 2018-01-30 US disclosed