SCHEMBL5651416

SCHEMBL5651416

CC1(C)C(=CC=CC=CC2=[N+](Cc3ccc(C(=O)O)cc3)c3ccc(S(=O)(=O)O)cc3C2(C)C)N(Cc2ccc(C(=O)O)cc2)c2ccc(S(=O)(=O)O)cc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 4/20 0.44
PTPN1 P18031 1/20 0.42
FOLH1 Q04609 1/20 0.41
NPY4R P50391 2/20 0.40
ADORA1 P30542 4/20 0.40
OPRK1 P41145 2/20 0.39
OPRM1 P35372 1/20 0.39
DPP8 Q6V1X1 1/20 0.39
DPP9 Q86TI2 1/20 0.39
TLR8 Q9NR97 1/20 0.38
MEN1 O00255 1/20 0.37
NPC1 O15118 1/20 0.37
USP2 O75604 1/20 0.37
S1PR2 O95136 1/20 0.37
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
ALPG P10696 1/20 0.37
THRB P10828 1/20 0.37
PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5651412 1.00 PRMT1 (0.44) PRMT1PTPN1FOLH1NPY4RADORA1
SCHEMBL13070158 0.92 PRMT1 (0.44) PRMT1PTPN1FOLH1NPY4RADORA1
SCHEMBL5653731 0.92 ADORA1 (0.41) PRMT1PTPN1FOLH1NPY4RADORA1
SCHEMBL5653734 0.92 ADORA1 (0.41) PRMT1PTPN1FOLH1NPY4RADORA1
SCHEMBL12602395 0.88 PRMT1 (0.53) PRMT1PTPN1FOLH1ADORA1OPRK1
SCHEMBL1709073 0.84 MEN1 (0.42) PRMT1PTPN1FOLH1NPY4RADORA1
SCHEMBL19820186 0.84 PRMT1 (0.56) PRMT1PTPN1MEN1NPC1USP2
SCHEMBL13050797 0.84 PRMT1 (0.38) PRMT1PTPN1FOLH1NPY4RADORA1
SCHEMBL1709066 0.83 PRMT1 (0.42) PRMT1PTPN1FOLH1NPY4RADORA1
SCHEMBL18271853 0.82 PTPN1 (0.47) PRMT1PTPN1FOLH1NPY4RADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060257917-A1 FLUORESCENT DYES, ENERGY TRANSFER COUPLES AND METHODS MILLIPORE CORPORATION 2006-11-16 US disclosed
US-7091348-B2 Fluorescent dyes, energy transfer couples and methods GUAVA TECHNOLOGIES, INC. (US) 2006-08-15 US disclosed
EP-1539728-A2 FLUORESCENT DYES, ENERGY TRANSFER COUPLES AND METHODS Guava Technologies, Inc. (US) 2005-06-15 EP disclosed
US-20040073014-A1 Fluorescent dyes, energy transfer couples and methods EMD MILLIPORE CORPORATION 2004-04-15 US disclosed
WO-2004003510-A2 FLUORESCENT DYES, ENERGY TRANSFER COUPLES AND METHODS GUAVA TECHNOLOGIES, INC. (US) 2004-01-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060257917-A1 FLUORESCENT DYES, ENERGY TRANSFER COUPLES AND METHODS TIMM50, TIMM44, APEX1 PRMT1 2167/4885PTPN1 4848/4885FOLH1 1190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.