Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Olumacostat Glasaretil SCHEMBL14856848 | 1.00 | MEN1 (0.54) | MEN1KMT2ATDP1LTA4HPPARA | |
| SCHEMBL19821453 | 1.00 | MEN1 (0.54) | MEN1KMT2ATDP1LTA4HPPARA | |
| SCHEMBL19821451 | 0.99 | MEN1 (0.53) | MEN1KMT2ATDP1LTA4HPPARA | |
| SCHEMBL19821455 | 0.93 | MEN1 (0.53) | MEN1KMT2ATDP1ALDH1A1NPC1 | |
| SCHEMBL19821448 | 0.90 | MEN1 (0.55) | MEN1KMT2ATDP1ALDH1A1NPC1 | |
| SCHEMBL19821449 | 0.90 | MEN1 (0.55) | MEN1KMT2ATDP1ALDH1A1NPC1 | |
| SCHEMBL19821447 | 0.90 | MEN1 (0.55) | MEN1KMT2ATDP1ALDH1A1NPC1 | |
| SCHEMBL19821444 | 0.90 | MEN1 (0.55) | MEN1KMT2ATDP1ALDH1A1NPC1 | |
| SCHEMBL19821445 | 0.90 | MEN1 (0.55) | MEN1KMT2ATDP1ALDH1A1NPC1 | |
| SCHEMBL19825249 | 0.84 | HDAC4 (0.40) | MEN1KMT2ATDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180028487-A1 | DERMATOLOGICAL FORMULATIONS OF 2-(2-ETHOXY-2-OXOETHYL)(METHYL)AMINO-2-OXOETHYL 5-(TETRADECYLOXY)FURAN-2-CARBOXYLATE | DERMIRA, INC. | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180028487-A1 | DERMATOLOGICAL FORMULATIONS OF 2-(2-ETHOXY-2-OXOETHYL)(METHYL)AMINO-2-OXOETHYL 5-(TETRADECYLOXY)FURAN-2-CARBOXYLATE | CUTA, CYP1A2, DPM1 | MEN1 3030/4885KMT2A 339/4885TDP1 2071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.