SCHEMBL19821859

SCHEMBL19821859

CCC(C)(C)C(=O)OCCCC(=O)NC

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.37
RECQL P46063 1/20 0.35
GAA P10253 1/20 0.35
LMNA P02545 1/20 0.34
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
ALDH1A1 P00352 2/20 0.33
PDK2 Q15119 1/20 0.32
PDE3B Q13370 1/20 0.30
PDE3A Q14432 1/20 0.30
P2RY12 Q9H244 1/20 0.30
FKBP1A P62942 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19822001 0.89 LMNA (0.36) EPHX1GAALMNACYP4F2CYP4A11
SCHEMBL19821918 0.83 KDM4E (0.34) RECQLGAACYP4F2CYP4A11ALDH1A1
SCHEMBL13667082 0.81 CYP4F2 (0.42) EPHX1CYP4F2CYP4A11ALDH1A1FKBP1A
SCHEMBL19821844 0.81 TSHR (0.48) RECQLLMNACYP4F2CYP4A11ALDH1A1
SCHEMBL2681601 0.80 AKR1B1 (0.40) LMNACYP4F2CYP4A11ALDH1A1PDE3A
SCHEMBL15450103 0.80 CYP4F2 (0.37) CYP4F2CYP4A11ALDH1A1FKBP1A
SCHEMBL26363345 0.80 CYP4F2 (0.37) LMNACYP4F2CYP4A11ALDH1A1FKBP1A
SCHEMBL13667073 0.79 CYP4F2 (0.46) EPHX1CYP4F2CYP4A11ALDH1A1TSHR
SCHEMBL19822040 0.79 KDM4E (0.40) EPHX1GAALMNACYP4F2CYP4A11
SCHEMBL19821858 0.78 KDM4E (0.37) GAALMNACYP4F2CYP4A11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230129965-A1 HYDROPHILIC AND OLEOPHOBIC POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-04-27 US disclosed
US-20180030175-A1 POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-01 US disclosed