SCHEMBL19822552

SCHEMBL19822552

[O-][S+](/C=C/CCN=C=S)C1CC1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 4/20 0.38
XPO1 O14980 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL994470 0.74 TRPA1 (0.43) TRPA1XPO1
SCHEMBL2937706 0.74 TRPA1 (0.43) TRPA1XPO1
SCHEMBL19822550 0.69 TRPA1 (0.38) TRPA1XPO1
SCHEMBL19822551 0.68 TRPA1 (0.37) TRPA1XPO1
SCHEMBL19822504 0.66 XPO1 (0.52) TRPA1XPO1
SCHEMBL21048436 0.66 XPO1 (0.52) TRPA1XPO1
SCHEMBL21048404 0.64 XPO1 (0.40) TRPA1XPO1
SCHEMBL19822516 0.64 XPO1 (0.40) TRPA1XPO1
SCHEMBL25332113 0.62
SCHEMBL5334903 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180029979-A1 ISOTHIOCYANATE COMPOUND AND APPLICATION THEREOF DRIVINGFORCE THERAPEUTICS Co., Ltd. (CN) 2018-02-01 US disclosed
US-20180029979-A1 ISOTHIOCYANATE COMPOUND AND APPLICATION THEREOF DRIVINGFORCE THERAPEUTICS Co., Ltd. (CN) 2018-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180029979-A1 ISOTHIOCYANATE COMPOUND AND APPLICATION THEREOF XPO1, XPOT, XPO4 TRPA1 248/4885XPO1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.