Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18852431 | 0.86 | ALDH1A1 (0.66) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL4668132 | 0.85 | ALDH1A1 (0.65) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL307289 | 0.83 | MAPT (0.58) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL306653 | 0.82 | MAPT (0.67) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL14817491 | 0.81 | ALDH1A1 (0.59) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL14580288 | 0.79 | ALDH1A1 (0.62) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL11317206 | 0.79 | ALDH1A1 (0.53) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL9886 | 0.78 | ALDH1A1 (0.85) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL19425986 | 0.78 | ALDH1A1 (0.85) | MAPTALDH1A1KMT2AMEN1GAA | |
| Acetic Acid SCHEMBL30876192 | 0.78 | NAPRT (0.64) | MAPTALDH1A1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3490975-B1 | O-SUBSTITUTED HYDROXAMIC ACIDS | UNIV JOHNS HOPKINS (US) | 2021-05-05 | — | — | EP | disclosed |
| WO-2018022899-A1 | O-SUBSTITUTED HYDROXAMIC ACIDS | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-02-01 | — | — | WO | disclosed |