Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 4/20 | 0.39 |
| ▸ | NOS3 | P29474 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19823007 | 0.91 | MAPT (0.43) | KMT2ANPC1RAB9AMAPTPSMD14 | |
| SCHEMBL9235923 | 0.91 | MAPT (0.43) | KMT2ANPC1RAB9AMAPTPSMD14 | |
| SCHEMBL12069741 | 0.88 | TDP1 (0.50) | KMT2ANPC1RAB9AMAPTPSMD14 | |
| SCHEMBL25485940 | 0.87 | KMT2A (0.65) | KMT2ANPC1RAB9AMAPTPSMD14 | |
| SCHEMBL19823016 | 0.85 | MAPT (0.40) | KMT2ANPC1RAB9AMAPTPSMD14 | |
| SCHEMBL16222277 | 0.83 | KMT2A (0.58) | KMT2ANPC1RAB9AMAPTPSMD14 | |
| SCHEMBL20566720 | 0.83 | KMT2A (0.58) | KMT2ANPC1RAB9AMAPTPSMD14 | |
| SCHEMBL19823003 | 0.82 | HTR3E (0.39) | KMT2ANPC1RAB9AMAPTPSMD14 | |
| SCHEMBL19822977 | 0.82 | SLC9A5 (0.40) | KMT2ANPC1RAB9AMAPTPSMD14 | |
| SCHEMBL4638072 | 0.81 | KMT2A (0.59) | KMT2ANPC1RAB9AMAPTPSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10731078-B2 | Composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-08-04 | — | — | US | disclosed |
| US-20180030354-A1 | COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-02-01 | — | — | US | disclosed |
| US-20180030354-A1 | COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-02-01 | — | — | US | disclosed |