Methylcaffeate

Methylcaffeate

SCHEMBL198252

COC(=O)C=Cc1ccc(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 6/20 1.00
TTR P02766 4/20 1.00
PTPN1 P18031 3/20 0.93
EPHX2 P34913 1/20 0.73
DPP4 P27487 2/20 0.69
CA12 O43570 2/20 0.66
CA1 P00915 2/20 0.66
CA2 P00918 2/20 0.66
CA7 P43166 2/20 0.66
CA9 Q16790 2/20 0.66
CA14 Q9ULX7 2/20 0.66
IAPP P10997 2/20 0.66
PTGS1 P23219 1/20 0.66
TYR P14679 1/20 0.66
HSD17B10 Q99714 3/20 0.62
KDM4E B2RXH2 2/20 0.62
TDP1 Q9NUW8 2/20 0.62
MMP1 P03956 2/20 0.62
MMP2 P08253 2/20 0.62
MMP9 P14780 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylcaffeate SCHEMBL30963730 1.00 APP (1.00) APPTTRPTPN1EPHX2DPP4
Methylcaffeate SCHEMBL817520 1.00 APP (1.00) APPTTRPTPN1EPHX2DPP4
Methylcaffeate SCHEMBL30637688 1.00 APP (1.00) APPTTRPTPN1EPHX2DPP4
Methylcaffeate SCHEMBL669440 0.94 APP (0.88) APPTTRPTPN1EPHX2DPP4
Methylcaffeate SCHEMBL28177340 0.92 APP (0.85) APPTTRPTPN1EPHX2DPP4
SCHEMBL30528020 0.88 TTR (0.79) APPTTRPTPN1EPHX2DPP4
Methylcaffeate SCHEMBL887921 0.87 APP (0.76) APPTTRPTPN1EPHX2DPP4
Methylcaffeate SCHEMBL30604508 0.87 APP (0.76) APPTTRPTPN1EPHX2DPP4
SCHEMBL12246161 0.86 APP (0.76) APPTTRPTPN1EPHX2DPP4
SCHEMBL9120636 0.86 APP (0.76) APPTTRPTPN1EPHX2DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 480 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120617206-B Ergosterol-loaded engineering exosome dual-drug-loading system and preparation method and application thereof 无锡市第二人民医院 2026-05-15 CN claimed
CN-119605396-A Method for improving seed germination under salt stress condition and application thereof 山东农业大学 2025-03-14 CN claimed
CN-119499232-A Application of gamma-linolenic acid and/or methyl caffeate in preparing medicament for treating diabetic nephropathy 山东中医药大学 2025-02-25 CN claimed
CN-119306595-A Method for preparing methyl caffeate 晨光生物科技集团股份有限公司 2025-01-14 CN claimed
CN-119139351-A Cytokine composition and application thereof in anti-aging weakness 知佰幸细胞库(浙江)有限公司 2024-12-17 CN claimed
CN-118374472-A Novel PET degrading enzyme excavation and application thereof 兰州大学 2024-07-23 CN claimed
CN-115737624-B Application of natural medicine in preparation of anti-Acinetobacter baumannii medicine 山东省妇幼保健院 2024-03-12 CN claimed
CN-117581873-A Application of cinnamic acid derivative in preventing and treating bacterial perforin disease of peach 广西特色作物研究院 2024-02-23 CN claimed
CN-116953100-A Construction method of Mahonia leaf characteristic map 华润三九现代中药制药有限公司 2023-10-27 CN claimed
CN-111377816-B Compound for promoting myocardial regeneration, its preparation method, medicinal products and application 健裕生技股份有限公司 2023-10-20 CN claimed
EP-1166782-A2 Anti-retroviral pharmaceutical compositions Yang, Chi-Chiang (TW) 2002-01-02 EP claimed
EP-1156775-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 2001-11-28 EP claimed
WO-2001078783-A2 COMPOSITIONS COMPRISING NATURAL AGENTS FOR TREATMENT OF CANCER HAUSER, INC. (US) 2001-10-25 WO claimed
US-6121269-A TOPICALLY APPLYING A PROTEIN-TYROSINE KINASE INHIBITOR TO SKIN TO REDUCE ANDROGEN-STIMULATED HAIR GROWTH WITHOUT SIDE EFFECTS GILLETTE COMPANY, THE, A DELAWARE CORPORATION 2000-09-19 US claimed
WO-2000050002-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 2000-08-31 WO claimed
EP-0374184-B1 CELL GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES BAYLOR COLLEGE MEDICINE (US) 1994-01-12 EP claimed
US-5216024-A Compounds such as methyl p-hydroxypenyllactate, derivatives BAYLOR COLLEGE OF MEDICINE (US) 1993-06-01 US claimed
WO-1993001824-A1 COMBINATION THERAPY USING BIOFLAVONOID COMPOUNDS WITH ANTI-CANCER DRUGS BAYLOR COLLEGE OF MEDICINE (US) 1993-02-04 WO claimed
EP-0374184-A1 CELL GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES. BAYLOR COLLEGE MEDICINE (US) 1990-06-27 EP claimed
WO-1989000849-A1 CELL GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES BAYLOR COLLEGE OF MEDICINE (US) 1989-02-09 WO claimed