Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 1.00 |
| ▸ | TTR | P02766 | 4/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.93 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.73 |
| ▸ | DPP4 | P27487 | 2/20 | 0.69 |
| ▸ | CA12 | O43570 | 2/20 | 0.66 |
| ▸ | CA1 | P00915 | 2/20 | 0.66 |
| ▸ | CA2 | P00918 | 2/20 | 0.66 |
| ▸ | CA7 | P43166 | 2/20 | 0.66 |
| ▸ | CA9 | Q16790 | 2/20 | 0.66 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.66 |
| ▸ | IAPP | P10997 | 2/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | TYR | P14679 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | MMP1 | P03956 | 2/20 | 0.62 |
| ▸ | MMP2 | P08253 | 2/20 | 0.62 |
| ▸ | MMP9 | P14780 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylcaffeate SCHEMBL30963730 | 1.00 | APP (1.00) | APPTTRPTPN1EPHX2DPP4 | |
| Methylcaffeate SCHEMBL198252 | 1.00 | APP (1.00) | APPTTRPTPN1EPHX2DPP4 | |
| Methylcaffeate SCHEMBL30637688 | 1.00 | APP (1.00) | APPTTRPTPN1EPHX2DPP4 | |
| Methylcaffeate SCHEMBL669440 | 0.94 | APP (0.88) | APPTTRPTPN1EPHX2DPP4 | |
| Methylcaffeate SCHEMBL28177340 | 0.92 | APP (0.85) | APPTTRPTPN1EPHX2DPP4 | |
| SCHEMBL30528020 | 0.88 | TTR (0.79) | APPTTRPTPN1EPHX2DPP4 | |
| Methylcaffeate SCHEMBL887921 | 0.87 | APP (0.76) | APPTTRPTPN1EPHX2DPP4 | |
| Methylcaffeate SCHEMBL30604508 | 0.87 | APP (0.76) | APPTTRPTPN1EPHX2DPP4 | |
| SCHEMBL12246161 | 0.86 | APP (0.76) | APPTTRPTPN1EPHX2DPP4 | |
| SCHEMBL9120636 | 0.86 | APP (0.76) | APPTTRPTPN1EPHX2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677647-A | Beta-bis-dioxolane anabasinic acid, preparation method and pharmaceutical application thereof | 吉林大学 | 2023-02-03 | — | — | CN | claimed |
| US-9611255-B2 | Process for total synthesis of flavonoid compounds and isomers thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-04-04 | — | — | US | claimed |
| US-20160362401-A1 | PROCESS FOR TOTAL SYNTHESIS OF FLAVONOID COMPOUNDS AND ISOMERS THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-12-15 | — | — | US | claimed |
| US-20150274633-A2 | PAIN RELIEF COMPOUNDS | UNIVERSITÉ CLERMONT AUVERGNE (FR) | 2015-10-01 | — | — | US | claimed |
| US-20150038466-A1 | PAIN RELIEF COMPOUNDS | ECOLE NATIONALE SUPERIEURE DE CHIMIE DE CLERMONT FERRAND (FR) | 2015-02-05 | — | — | US | claimed |
| EP-2061452-B1 | ANTI CANCER USE OF CAFFEIC ACID AND DERIVATIVES | PIRAMAL LIFE SCIENCES LTD (IN) | 2011-10-26 | — | — | EP | claimed |
| CN-101774918-A | Preparation method of cinnamate derivates | UNIV HUAQIAO | 2010-07-14 | — | — | CN | claimed |
| US-20100010002-A1 | ANTICANCER USE OF CAFFEIC ACID AND ITS DERIVATIVES | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2010-01-14 | — | — | US | claimed |
| EP-2061452-A2 | ANTI CANCER USE OF CAFFEIC ACID AND DERIVATIVES | Piramal Life Sciences Limited (IN) | 2009-05-27 | — | — | EP | claimed |
| WO-2008026125-A2 | ANTI CANCER USE OF CAFFEIC ACID AND DERIVATIVES | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2008-03-06 | — | — | WO | claimed |
| EP-0374184-B1 | CELL GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES | BAYLOR COLLEGE MEDICINE (US) | 1994-01-12 | — | — | EP | claimed |
| US-5216024-A | Compounds such as methyl p-hydroxypenyllactate, derivatives | BAYLOR COLLEGE OF MEDICINE (US) | 1993-06-01 | — | — | US | claimed |
| WO-1993001824-A1 | COMBINATION THERAPY USING BIOFLAVONOID COMPOUNDS WITH ANTI-CANCER DRUGS | BAYLOR COLLEGE OF MEDICINE (US) | 1993-02-04 | — | — | WO | claimed |
| EP-0374184-A1 | CELL GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES. | BAYLOR COLLEGE MEDICINE (US) | 1990-06-27 | — | — | EP | claimed |
| WO-1989000849-A1 | CELL GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES | BAYLOR COLLEGE OF MEDICINE (US) | 1989-02-09 | — | — | WO | claimed |
| CN-114910586-B | Method for determining caffeic acid and its derivatives content in Monascus purpureus extract | 上海医药工业研究院有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117581873-A | Application of cinnamic acid derivative in preventing and treating bacterial perforin disease of peach | 广西特色作物研究院 | 2024-02-23 | — | — | CN | disclosed |
| WO-1991017749-A1 | GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES | BAYLOR COLLEGE OF MEDICINE (US) | 1991-11-28 | — | — | WO | disclosed |
| EP-0374184-A1 | CELL GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES. | BAYLOR COLLEGE MEDICINE (US) | 1990-06-27 | — | — | EP | disclosed |
| WO-1989000849-A1 | CELL GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES | BAYLOR COLLEGE OF MEDICINE (US) | 1989-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160362401-A1 | PROCESS FOR TOTAL SYNTHESIS OF FLAVONOID COMPOUNDS AND ISOMERS THEREOF | UGT1A3, F3, UGGT1 | APP 3980/4885TTR 1911/4885PTPN1 4531/4885 |
| US-20100010002-A1 | ANTICANCER USE OF CAFFEIC ACID AND ITS DERIVATIVES | ABL1, MCL1, SRC | APP 4524/4885TTR 2069/4885PTPN1 53/4885 |
| US-20150038466-A1 | PAIN RELIEF COMPOUNDS | OPRL1, OPRK1, TRPV1 | APP 3114/4885TTR 1663/4885PTPN1 4797/4885 |
| US-20150274633-A2 | PAIN RELIEF COMPOUNDS | OPRL1, OPRK1, TRPV1 | APP 3114/4885TTR 1663/4885PTPN1 4797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.