Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 20/20 | 0.85 |
| ▸ | TPH2 | Q8IWU9 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19827088 | 0.92 | TPH1 (1.00) | TPH1TPH2 | |
| SCHEMBL19827158 | 0.91 | TPH1 (1.00) | TPH1TPH2 | |
| SCHEMBL19827087 | 0.85 | TPH1 (1.00) | TPH1TPH2 | |
| SCHEMBL19817439 | 0.85 | TPH1 (1.00) | TPH1TPH2 | |
| SCHEMBL19817198 | 0.85 | TPH1 (1.00) | TPH1TPH2 | |
| SCHEMBL19817153 | 0.83 | TPH1 (1.00) | TPH1TPH2 | |
| SCHEMBL19810118 | 0.82 | TPH1 (1.00) | TPH1TPH2 | |
| SCHEMBL19813992 | 0.82 | TPH1 (1.00) | TPH1TPH2 | |
| SCHEMBL19817149 | 0.80 | TPH1 (1.00) | TPH1TPH2 | |
| SCHEMBL19810115 | 0.78 | TPH1 (1.00) | TPH1TPH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3490996-B1 | XANTHINE DERIVATIVES, THEIR USE AS A MEDICAMENT, AND PHARMACEUTICAL PREPARATIONS COMPRISING THE SAME | MAX DELBRUECK CENTRUM FUER MOLEKULARE MEDIZIN (DE) | 2020-08-26 | — | — | EP | disclosed |
| WO-2018019917-A1 | XANTHINE DERIVATIVES, THEIR USE AS A MEDICAMENT, AND PHARMACEUTICAL PREPARATIONS COMPRISING THE SAME | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 2018-02-01 | — | — | WO | disclosed |