Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 3/20 | 0.38 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.35 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19186747 | 0.89 | NT5E (0.41) | NT5EFUT5IMPDH2IMPDH1P2RY1 | |
| SCHEMBL19827519 | 0.86 | NT5E (0.37) | NT5EFUT5IMPDH2IMPDH1P2RY1 | |
| SCHEMBL19525764 | 0.85 | ADORA1 (0.37) | NT5E | |
| SCHEMBL19827534 | 0.84 | NT5E (0.36) | NT5EFUT5IMPDH2IMPDH1P2RY1 | |
| SCHEMBL23010227 | 0.83 | NT5E (0.38) | NT5EP2RY1P2RY11 | |
| SCHEMBL19187036 | 0.82 | NT5E (0.41) | NT5EFUT5IMPDH2IMPDH1P2RY1 | |
| SCHEMBL19827565 | 0.81 | NT5E (0.38) | NT5EFUT5IMPDH2IMPDH1P2RY1 | |
| SCHEMBL20056907 | 0.80 | NT5E (0.40) | NT5EFUT5IMPDH2IMPDH1P2RY1 | |
| SCHEMBL19186685 | 0.79 | NT5E (0.32) | NT5E | |
| SCHEMBL19392093 | 0.79 | CYP3A4 (0.44) | NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2852605-B1 | 3',5'-CYCLIC PHOSPHATE PRODRUGS FOR HCV INFECTION | IDENIX PHARMACEUTICALS LLC (US) | 2018-01-31 | — | — | EP | disclosed |