SCHEMBL198282

SCHEMBL198282

COC(=O)Cc1ccc(OC)c(OC)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.62
ABL1 P00519 1/20 0.60
RIN1 Q13671 1/20 0.60
LMNA P02545 4/20 0.59
HTT P42858 3/20 0.59
NPC1 O15118 1/20 0.59
EPHX2 P34913 1/20 0.59
GAA P10253 5/20 0.58
MAPT P10636 3/20 0.58
CYP1A2 P05177 1/20 0.58
CYP3A4 P08684 1/20 0.58
CYP2C19 P33261 1/20 0.58
KMT2A Q03164 2/20 0.58
MEN1 O00255 1/20 0.58
HPGD P15428 1/20 0.58
LDHA P00338 1/20 0.57
GLA P06280 1/20 0.57
CA2 P00918 1/20 0.57
SMN1; SMN2 Q16637 2/20 0.56
POLB P06746 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29626821 1.00 ALDH1A1 (0.62) ALDH1A1ABL1RIN1LMNAHTT
SCHEMBL18887599 0.89 TSHR (0.56) ALDH1A1ABL1RIN1LMNAGAA
SCHEMBL17124777 0.87 JAK2 (0.55) ALDH1A1ABL1RIN1LMNAHTT
SCHEMBL9000738 0.87 ABL1 (0.49) ALDH1A1ABL1RIN1LMNAHTT
SCHEMBL9000521 0.87 ABL1 (0.52) ALDH1A1ABL1RIN1LMNAHTT
SCHEMBL2987951 0.86 NPSR1 (0.48) ALDH1A1ABL1RIN1LMNAHTT
SCHEMBL3759057 0.86 GAA (0.53) ALDH1A1ABL1RIN1LMNANPC1
SCHEMBL2094025 0.86 GAA (0.53) ALDH1A1ABL1RIN1EPHX2GAA
SCHEMBL13813952 0.86 ALDH1A1 (0.53) ALDH1A1ABL1RIN1LMNANPC1
SCHEMBL30094581 0.86 GAA (0.53) ALDH1A1ABL1RIN1LMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107033006-B Preparation method of diaryl ketone 长沙理工大学 2018-12-18 CN claimed
CN-107033006-A Preparation method of diaryl ketone 长沙理工大学 2017-08-11 CN claimed
CN-102924318-B L-leucine derivatives blocking entrance of H5N1 avian influenza virus and preparation method for same UNIV WUHAN 2014-06-04 CN claimed
CN-102924318-A L-leucine derivatives blocking entrance of H5N1 avian influenza virus and preparation method for same UNIV WUHAN 2013-02-13 CN claimed
EP-4734977-A2 NOVEL TRPV1 AGONISTS AND USES THEREOF Neucures, Inc. (US) 2026-05-06 EP disclosed
EP-4616906-A2 BENZO[A]PHENANTHRIDINE DERIVATIVES AS YAP/TAZ INHIBITORS Sanford Burnham Prebys Medical Discovery Institute (US) 2025-09-17 EP disclosed
US-20250195462-A1 SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF MILESTONE PHARMACEUTICALS INC (CA) 2025-06-19 US disclosed
WO-2025006675-A9 NOVEL TRPV1 AGONISTS AND USES THEREOF NEUCURES, INC. (US) 2025-03-13 WO disclosed
WO-2025006675-A2 NOVEL TRPV1 AGONISTS AND USES THEREOF NEUCURES, INC. (US) 2025-01-02 WO disclosed
US-20240366552-A1 SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF MILESTONE PHARMACEUTICALS INC (CA) 2024-11-07 US disclosed
WO-2024183784-A1 PHARMACEUTICAL USE OF TROPIC ACID AND DERIVATIVES THEREOF IN PREPARATION OF DRUG FOR TREATING IMMUNE- AND INFLAMMATION-RELATED DISEASES 广东药科大学 2024-09-12 WO disclosed
WO-2024088153-A1 USE OF TROPIC ACID AND DERIVATIVE THEREOF IN PREPARATION OF DRUG FOR TREATING PSORIASIS 广东药科大学 2024-05-02 WO disclosed
EP-0611003-A1 Substituted phenyl sulfonamides as selective B3 agonists for the treatment of diabetes and obesity MERCK & CO. INC. (US) 1994-08-17 EP disclosed
US-RE34630-E Antagonist for platelet activating factor EUROCELTIQUE, S.A. (LU) 1994-06-07 US disclosed
US-5243066-A ALKYL 2-ARYL-2,2-DIALKOXYACETATES, THE PREPARATION THEREOF AND A METHOD OF USING THEM FOR PREPARING ARYLGLYOXYLIC ESTERS BASF AKTIENGESELLSCHAFT (DE) 1993-09-07 US disclosed
US-5219848-A Bactericides ICI PHARMA (FR) 1993-06-15 US disclosed
EP-0422328-A2 Substituted isoquinolines and their use Euro-Celtique S.A. (LU) 1991-04-17 EP disclosed
EP-0412763-A2 Cephalosporins, processes for their preparation, pharmaceutical compositions containing them and intermediates therefor ZENECA LIMITED (GB) 1991-02-13 EP disclosed
US-4956371-A PLATELET ACTIVATING FACTOR EUROCELTIQUE, S.A. (LU) 1990-09-11 US disclosed
US-3936457-A VASODILATION WARNER-LAMBERT COMPANY (US) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240366552-A1 SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF ORAI1, ATP2A1, RYR2 ALDH1A1 3189/4885ABL1 1470/4885RIN1 4325/4885
US-20250195462-A1 SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF ORAI1, ATP2A1, RYR2 ALDH1A1 3189/4885ABL1 1470/4885RIN1 4325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.