Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19824617 | 0.85 | ADORA1 (0.38) | TDP1ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL12971765 | 0.85 | ADORA1 (0.36) | TDP1ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL21258707 | 0.85 | ADORA1 (0.36) | TDP1ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL1505410 | 0.85 | ADORA1 (0.36) | TDP1ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL20015462 | 0.85 | KDM4E (0.38) | TDP1ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL12971746 | 0.84 | TDP1 (0.38) | TDP1ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL1505321 | 0.84 | TDP1 (0.38) | TDP1ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL10119510 | 0.84 | NPC1 (0.39) | ADORA1ADORA2AALDH1A1XDHGSK3B | |
| SCHEMBL19824644 | 0.83 | PDGFRB (0.39) | TDP1ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL1293548 | 0.83 | AR (0.33) | PDGFRBGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3262030-B1 | PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF ELUXADOLINE | ALLERGAN HOLDINGS UNLIMITED COMPANY (IE) | 2019-09-11 | — | — | EP | disclosed |
| US-20180029994-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF ELUXADOLINE | ALLERGAN HOLDINGS UNLIMITED COMPANY (IE) | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180029994-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF ELUXADOLINE | OPRM1, ELP1, ELAVL1 | TDP1 349/4885ADORA1 1234/4885ADORA3 1574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.