Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.53 |
| ▸ | RARA | P10276 | 2/20 | 0.53 |
| ▸ | RARG | P13631 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19829090 | 0.95 | RARB (0.48) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL18310412 | 0.91 | RARB (0.51) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL9399575 | 0.90 | RARB (0.55) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL18310378 | 0.89 | RARB (0.40) | RARBRARARARGHSD17B10ALDH1A1 | |
| SCHEMBL18310416 | 0.89 | RARB (0.40) | RARBRARARARGHSD17B10ALDH1A1 | |
| SCHEMBL9399219 | 0.88 | RARB (0.57) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL9399803 | 0.88 | RARB (0.57) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL12358132 | 0.87 | RAB9A (0.58) | RARBRARARARGHSD17B10ALDH1A1 | |
| SCHEMBL18310411 | 0.86 | RARB (0.46) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL19829128 | 0.86 | RARB (0.42) | RARBRARARARGHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180030351-A1 | LIQUID CRYSTAL COMPOUND HAVING POLYFLUORO-2-BUTENOXY GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2018-02-01 | — | — | US | disclosed |