SCHEMBL19829098

SCHEMBL19829098

CCCc1ccc(-c2cc(F)c(C(F)(F)Oc3cc(F)c(OCF)c(F)c3)c(F)c2)c(F)c1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 2/20 0.32
S1PR3 Q99500 2/20 0.32
FFAR4 Q5NUL3 2/20 0.31
FFAR1 O14842 1/20 0.31
PDK2 Q15119 1/20 0.31
PTGS2 P35354 1/20 0.31
GRM2 Q14416 1/20 0.31
ALOX5AP P20292 1/20 0.30
FEN1 P39748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18310587 0.98 FFAR1 (0.34) S1PR1S1PR3FFAR4FFAR1PDK2
SCHEMBL19829208 0.98 ALOX5AP (0.33) S1PR1S1PR3FFAR4FFAR1PDK2
SCHEMBL19829192 0.97 FFAR1 (0.35) S1PR1S1PR3FFAR4FFAR1PDK2
SCHEMBL19829223 0.96 S1PR1 (0.30) S1PR1S1PR3
SCHEMBL19829206 0.94 S1PR1 (0.35) S1PR1S1PR3FFAR4FFAR1GRM2
SCHEMBL18310565 0.93 FFAR1 (0.32) S1PR1S1PR3FFAR4FFAR1GRM2
SCHEMBL19829119 0.93 PTGS2 (0.30) S1PR1S1PR3PTGS2GRM2
SCHEMBL19829222 0.93 S1PR1 (0.34) S1PR1S1PR3FFAR4FFAR1GRM2
SCHEMBL19829164 0.92
SCHEMBL18310569 0.91 S1PR1 (0.33) S1PR1S1PR3FFAR4FFAR1GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180030351-A1 LIQUID CRYSTAL COMPOUND HAVING POLYFLUORO-2-BUTENOXY GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-02-01 US disclosed