SCHEMBL19829131

SCHEMBL19829131

CCCCCC1COC(c2ccc(C(=O)Oc3cc(F)c(OCF)c(F)c3)c(F)c2)OC1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.32
HIF1A Q16665 1/20 0.31
RARA P10276 1/20 0.31
RARB P10826 1/20 0.31
PARP15 Q460N3 1/20 0.30
PARP10 Q53GL7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19829198 0.94 HIF1A (0.32) HIF1APARP15PARP10
SCHEMBL19829129 0.82
SCHEMBL18310547 0.80
SCHEMBL19829139 0.80
SCHEMBL16545505 0.80 HIF1A (0.32) HIF1A
SCHEMBL19829095 0.77
SCHEMBL12626579 0.76 RARB (0.34) RARARARB
SCHEMBL15744797 0.76 HIF1A (0.31) HIF1A
SCHEMBL19829121 0.76
SCHEMBL14224653 0.76 RARB (0.43) RARARARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180030351-A1 LIQUID CRYSTAL COMPOUND HAVING POLYFLUORO-2-BUTENOXY GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-02-01 US disclosed