Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.43 |
| ▸ | RARA | P10276 | 3/20 | 0.43 |
| ▸ | RARG | P13631 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 4/20 | 0.34 |
| ▸ | RXRB | P28702 | 3/20 | 0.34 |
| ▸ | RXRG | P48443 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150818 | 0.83 | HTR2A (0.35) | — | |
| SCHEMBL10548434 | 0.81 | RARB (0.43) | RARBRARARARGPPARARXRA | |
| SCHEMBL14197212 | 0.81 | — | — | |
| SCHEMBL27938626 | 0.80 | SLC6A2 (0.35) | — | |
| SCHEMBL27920144 | 0.80 | KDM1A (0.42) | — | |
| SCHEMBL27920142 | 0.80 | KDM1A (0.42) | — | |
| SCHEMBL27920141 | 0.80 | SLC6A2 (0.35) | — | |
| SCHEMBL8997261 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL9785326 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL9578525 | 0.79 | RARB (0.41) | RARBRARAKMT2ATHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7354950-B2 | 1,3-Dioxane derivatives, composition, optical element and display device containing the same | FUJIFILM CORPORATION (JP) | 2008-04-08 | — | — | US | disclosed |
| US-20070194278-A1 | 1,3-Dioxane derivatives, composition, optical element and display device containing the same | FUJIFILM CORPORATION | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070194278-A1 | 1,3-Dioxane derivatives, composition, optical element and display device containing the same | DDR1, CRY1, CXCR1 | RARB 125/4885RARA 60/4885RARG 290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.