SCHEMBL19829155

SCHEMBL19829155

CCCc1ccc(-c2ccc(-c3ccc(C(F)(F)Oc4cc(F)c(OCF)c(F)c4)cc3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.35
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33
PKM P14618 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
FFAR4 Q5NUL3 4/20 0.32
ACACB O00763 1/20 0.32
ACACA Q13085 1/20 0.32
PSMB5 P28074 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31
RARB P10826 2/20 0.31
RARA P10276 1/20 0.31
RARG P13631 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19829202 0.92 S1PR1 (0.36) MAOBRARBRARARARGS1PR1
SCHEMBL19829204 0.91 S1PR1 (0.35) NPC1TP53PKMRAB9ASMN1; SMN2
SCHEMBL19829108 0.90 FFAR4 (0.35) MAOBFFAR4RXRARXRBRXRG
SCHEMBL19829125 0.90 MAOB (0.39) MAOBFFAR4
SCHEMBL19829163 0.88 RARB (0.32) NPC1TP53PKMRAB9ASMN1; SMN2
SCHEMBL18310368 0.88 RARB (0.32) NPC1TP53PKMRAB9ASMN1; SMN2
SCHEMBL19829156 0.88 S1PR1 (0.36) MAOBFFAR4PSMB5SENP8SENP7
SCHEMBL19829112 0.87 KIF11 (0.39) NPC1TP53PKMRAB9ASMN1; SMN2
SCHEMBL19829147 0.87 KIF11 (0.39) NPC1TP53PKMRAB9ASMN1; SMN2
SCHEMBL15339479 0.86 MAOB (0.39) MAOBNPC1TP53PKMRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180030351-A1 LIQUID CRYSTAL COMPOUND HAVING POLYFLUORO-2-BUTENOXY GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-02-01 US disclosed