Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.66 |
| ▸ | IGF1R | P08069 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810012 | 0.85 | ADORA1 (0.73) | ADORA1IGF1RMAPK1MAPK14MAPK3 | |
| SCHEMBL8639797 | 0.84 | ADORA1 (0.72) | ADORA1IGF1RMAPK1EGFRHTT | |
| SCHEMBL7304113 | 0.84 | ADORA1 (0.68) | ADORA1IGF1RMAPK1PDE4BPDE3A | |
| SCHEMBL7301059 | 0.83 | ADORA1 (0.67) | ADORA1IGF1RMAPK1MAPK14MAPK3 | |
| SCHEMBL7299166 | 0.83 | ADORA1 (0.77) | ADORA1IGF1RMAPK1MAPK14MAPK3 | |
| SCHEMBL7295203 | 0.83 | ADORA1 (0.73) | ADORA1IGF1RMAPK1MAPK14MAPK3 | |
| Hydrochloric Acid SCHEMBL7301696 | 0.81 | ADORA1 (0.68) | ADORA1IGF1RMAPK1MAPK14MAPK3 | |
| SCHEMBL8808692 | 0.81 | ADORA1 (0.80) | ADORA1IGF1RMAPK1MAPK14MAPK3 | |
| SCHEMBL8807266 | 0.81 | ADORA1 (0.88) | ADORA1IGF1RMAPK1AKT1HTT | |
| SCHEMBL8809138 | 0.81 | ADORA1 (0.64) | ADORA1IGF1RMAPK1MAPK14MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180030453-A1 | METHOD FOR IMPROVING LEARNING | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180030453-A1 | METHOD FOR IMPROVING LEARNING | NT5E, ADORA1, ENTPD5 | ADORA1 2/4885IGF1R 763/4885MAPK1 3104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.