SCHEMBL19829502

SCHEMBL19829502

Cc1cc(-c2cccc(-c3ccc4ccc(-c5cccc(-c6cc(C)c7cccnc7n6)c5)cc4c3)c2)nc2ncccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 3/20 0.44
ACHE P22303 3/20 0.44
SYK P43405 1/20 0.40
CCR1 P32246 1/20 0.39
CCR8 P51685 1/20 0.39
DHODH Q02127 1/20 0.39
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
THRB P10828 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CYP17A1 P05093 2/20 0.36
CYP11B2 P19099 2/20 0.36
SIRT2 Q8IXJ6 1/20 0.36
NPC1 O15118 1/20 0.36
POLB P06746 1/20 0.36
RAB9A P51151 1/20 0.36
CYP19A1 P11511 1/20 0.36
CYP11B1 P15538 1/20 0.36
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19829496 0.92 CCR1 (0.41) BCHEACHESYKCCR1CCR8
SCHEMBL19829493 0.82 CCR1 (0.41) BCHEACHECCR1CCR8DHODH
SCHEMBL15976491 0.82 ALDH1A1 (0.49) BCHEACHECCR1CCR8DHODH
SCHEMBL14034363 0.76 KDM4E (0.56) SYKDHODHALDH1A1MAPTTDP1
SCHEMBL14241409 0.74 CCR1 (0.50) BCHEACHECCR1CCR8
SCHEMBL15976490 0.73 KDM4E (0.49) CCR1CCR8ALDH1A1MAPTTDP1
SCHEMBL22096279 0.71 DHODH (0.40) BCHEACHESYKDHODHALDH1A1
SCHEMBL14227400 0.70 CYP1A2 (0.52) ACHECCR1CCR8DHODHALDH1A1
SCHEMBL15460614 0.69 BCHE (0.57) BCHEACHEDHODHALDH1A1KDM4E
SCHEMBL10032927 0.69 ABL1 (0.42) DHODHALDH1A1CYP17A1CYP11B2SIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10686150-B2 Organic light emitting device LG CHEM, LTD. (KR) 2020-06-16 US disclosed
US-20180033989-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2018-02-01 US disclosed
US-20180033989-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2018-02-01 US disclosed