Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 19/20 | 1.00 |
| ▸ | ADORA1 | P30542 | 12/20 | 1.00 |
| ▸ | ADORA2B | P29275 | 10/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gw-328267 SCHEMBL1980933 | 1.00 | ADORA2A (1.00) | ADORA2AADORA3ADORA1ADORA2B | |
| Gw-328267 SCHEMBL1979140 | 1.00 | ADORA2A (1.00) | ADORA2AADORA3ADORA1ADORA2B | |
| Gw-328267 SCHEMBL1983128 | 1.00 | ADORA2A (1.00) | ADORA2AADORA3ADORA1ADORA2B | |
| Gw-328267 SCHEMBL29369354 | 1.00 | ADORA2A (1.00) | ADORA2AADORA3ADORA1ADORA2B | |
| Gw-328267 SCHEMBL13268529 | 1.00 | ADORA2A (1.00) | ADORA2AADORA3ADORA1ADORA2B | |
| Gw-328267 SCHEMBL4390982 | 1.00 | ADORA2A (1.00) | ADORA2AADORA3ADORA1ADORA2B | |
| Gw-328267 SCHEMBL13268494 | 1.00 | ADORA2A (1.00) | ADORA2AADORA3ADORA1ADORA2B | |
| Gw-328267 SCHEMBL5089293 | 0.99 | ADORA2A (0.99) | ADORA2AADORA3ADORA1ADORA2B | |
| Gw-328267 SCHEMBL7228505 | 0.96 | ADORA2A (0.93) | ADORA2AADORA3ADORA1ADORA2B | |
| Gw-328267 SCHEMBL7224617 | 0.96 | ADORA2A (0.93) | ADORA2AADORA3ADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011069918-A1 | NOVEL MEDICAL USE | GLAXO GROUP LIMITED (GB) | 2011-06-16 | — | — | WO | disclosed |
| US-6426337-B1 | ANTIINFLAMMATORY AGENTS | SMITHKLINE BEECHAM CORPORATION | 2002-07-30 | — | — | US | disclosed |