Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.72 |
| ▸ | NPC1 | O15118 | 13/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | STAT3 | P40763 | 1/20 | 0.72 |
| ▸ | CASP3 | P42574 | 1/20 | 0.72 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.72 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.72 |
| ▸ | APP | P05067 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | KDM5A | P29375 | 1/20 | 0.58 |
| ▸ | KDM5C | P41229 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2193986 | 1.00 | RAB9A (0.72) | RAB9ANPC1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL1984138 | 0.92 | RAB9A (0.84) | RAB9ANPC1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL12422082 | 0.89 | RAB9A (0.61) | RAB9ANPC1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL2194990 | 0.85 | RAB9A (0.58) | RAB9ANPC1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL2194986 | 0.85 | RAB9A (0.58) | RAB9ANPC1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9788664 | 0.84 | RAB9A (1.00) | RAB9ANPC1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL10172979 | 0.82 | RAB9A (0.86) | RAB9ANPC1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL1984672 | 0.82 | RAB9A (0.52) | RAB9ANPC1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL1984676 | 0.82 | RAB9A (0.52) | RAB9ANPC1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL1985017 | 0.81 | RAB9A (0.51) | RAB9ANPC1ALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338059-B1 | Ligands for aggregated tau molecules | WISTA LAB LTD (SG) | 2015-04-08 | — | — | EP | disclosed |
| US-8895313-B2 | Ligands for aggregated tau molecules | WISTA LABORATORIES LTD. (SG) | 2014-11-25 | — | — | US | disclosed |
| US-20110171739-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | WISTA LABORATORIES LTD. | 2011-07-14 | — | — | US | disclosed |
| EP-2338059-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | Wista Laboratories Ltd. (SG) | 2011-06-29 | — | — | EP | disclosed |
| WO-2010034982-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | WISTA LABORATORIES LTD. (SG) | 2010-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171739-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | MAPT, PRNP, MAP4 | RAB9A 2622/4885NPC1 1265/4885ALDH1A1 2058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.