Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19838576 | 1.00 | CTDSP1 (0.46) | CTDSP1TDP1POLBMAPTLMNA | |
| SCHEMBL29960412 | 1.00 | CTDSP1 (0.46) | CTDSP1TDP1POLBMAPTLMNA | |
| SCHEMBL7917078 | 0.88 | CTDSP1 (0.44) | CTDSP1TDP1POLBMAPTLMNA | |
| SCHEMBL21538712 | 0.82 | CTDSP1 (0.47) | CTDSP1TDP1POLBMAPTLMNA | |
| SCHEMBL7395455 | 0.82 | RXRA (0.49) | CTDSP1TDP1MAPTLMNAMDM2 | |
| SCHEMBL5479417 | 0.82 | RXRA (0.49) | CTDSP1TDP1MAPTLMNAMDM2 | |
| SCHEMBL7395451 | 0.82 | RXRA (0.49) | CTDSP1TDP1MAPTLMNAMDM2 | |
| SCHEMBL7399953 | 0.81 | SMN1; SMN2 (0.51) | CTDSP1TDP1POLBMAPTLMNA | |
| SCHEMBL31660724 | 0.81 | SMN1; SMN2 (0.51) | CTDSP1TDP1POLBMAPTLMNA | |
| SCHEMBL5479497 | 0.81 | SMN1; SMN2 (0.51) | CTDSP1TDP1POLBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026371-A1 | DUAL NAV1.2/5HT2A INHIBITORS FOR TREATING CNS DISORDERS | SUNOVION PHARMACEUTICALS INC. (US) | 2018-02-08 | — | — | WO | disclosed |