Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16755523 | 1.00 | DRD3 (0.50) | DRD3ACHEMEN1KMT2ACYP1A2 | |
| SCHEMBL16755522 | 1.00 | DRD3 (0.50) | DRD3ACHEMEN1KMT2ACYP1A2 | |
| SCHEMBL16755573 | 0.93 | MEN1 (0.54) | ACHEMEN1KMT2ACYP1A2PKM | |
| SCHEMBL15561391 | 0.93 | MEN1 (0.54) | ACHEMEN1KMT2ACYP1A2PKM | |
| SCHEMBL19840311 | 0.93 | MEN1 (0.54) | ACHEMEN1KMT2ACYP1A2PKM | |
| SCHEMBL16769871 | 0.86 | GPR183 (0.52) | ACHEMEN1KMT2ACYP1A2PKM | |
| SCHEMBL19840309 | 0.86 | ACHE (0.48) | ACHEMEN1KMT2ACYP1A2PKM | |
| SCHEMBL16755567 | 0.86 | ACHE (0.48) | ACHEMEN1KMT2ACYP1A2PKM | |
| SCHEMBL15562263 | 0.86 | GPR183 (0.52) | ACHEMEN1KMT2ACYP1A2PKM | |
| SCHEMBL15562261 | 0.86 | GPR183 (0.52) | ACHEMEN1KMT2ACYP1A2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884825-B2 | Curcumin analogs and methods of making and using thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2018-02-06 | — | — | US | disclosed |
| US-9884825-B2 | Curcumin analogs and methods of making and using thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2018-02-06 | — | — | US | disclosed |