Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD4 | P01730 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15562368 | 1.00 | CD4 (0.47) | CD4CNR2ACHEDRD3SMN1; SMN2 | |
| SCHEMBL15562369 | 1.00 | CD4 (0.47) | CD4CNR2ACHEDRD3SMN1; SMN2 | |
| SCHEMBL16755539 | 0.93 | ACHE (0.46) | CD4CNR2ACHEDRD3MEN1 | |
| SCHEMBL16755536 | 0.93 | ACHE (0.46) | CD4CNR2ACHEDRD3MEN1 | |
| SCHEMBL19840308 | 0.93 | ACHE (0.46) | CD4CNR2ACHEDRD3MEN1 | |
| SCHEMBL16769879 | 0.89 | KMT2A (0.47) | CNR2ACHEDRD3SMN1; SMN2LMNA | |
| SCHEMBL16755544 | 0.89 | KMT2A (0.47) | CNR2ACHEDRD3SMN1; SMN2LMNA | |
| SCHEMBL16755542 | 0.89 | KMT2A (0.47) | CNR2ACHEDRD3SMN1; SMN2LMNA | |
| SCHEMBL19840306 | 0.88 | ACHE (0.48) | CD4ACHELMNAMEN1KMT2A | |
| SCHEMBL16755587 | 0.88 | ACHE (0.48) | CD4ACHELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884825-B2 | Curcumin analogs and methods of making and using thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2018-02-06 | — | — | US | disclosed |
| US-9884825-B2 | Curcumin analogs and methods of making and using thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2018-02-06 | — | — | US | disclosed |