Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 2/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12590139 | 0.88 | CHEK1 (0.33) | CHEK1PRKCADYRK1APAX8 | |
| SCHEMBL12646765 | 0.88 | CHEK1 (0.33) | CHEK1PRKCADYRK1APAX8 | |
| SCHEMBL19884481 | 0.86 | ADORA1 (0.35) | — | |
| SCHEMBL19840324 | 0.85 | P2RY14 (0.35) | — | |
| SCHEMBL19840325 | 0.84 | — | — | |
| SCHEMBL23353386 | 0.82 | TK2 (0.37) | — | |
| SCHEMBL14510444 | 0.82 | TK2 (0.37) | — | |
| SCHEMBL21283066 | 0.82 | TK2 (0.37) | — | |
| SCHEMBL21283173 | 0.76 | CDA (0.47) | — | |
| SCHEMBL24052323 | 0.75 | PRKCA (0.31) | PRKCADYRK1APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9885036-B2 | Double-stranded polynucleotide | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-02-06 | — | — | US | disclosed |