Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.34 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12920215 | 0.96 | ADORA3 (0.36) | ADORA3ADORA1ADORA2AP2RY12DOT1L | |
| SCHEMBL412698 | 0.96 | ADORA3 (0.36) | ADORA3ADORA1ADORA2AP2RY12DOT1L | |
| SCHEMBL12920235 | 0.88 | ADORA3 (0.33) | ADORA3ADORA1ADORA2AP2RY12DOT1L | |
| SCHEMBL16572309 | 0.88 | ADORA3 (0.33) | ADORA3ADORA1ADORA2AP2RY12DOT1L | |
| SCHEMBL16245122 | 0.84 | ADORA3 (0.38) | ADORA3ADORA1ADORA2A | |
| SCHEMBL19840345 | 0.83 | ADORA3 (0.47) | ADORA3ADORA1ADORA2AP2RY12 | |
| SCHEMBL12920212 | 0.81 | ADORA3 (0.45) | ADORA3ADORA1ADORA2AP2RY12 | |
| SCHEMBL411677 | 0.81 | ADORA3 (0.45) | ADORA3ADORA1ADORA2AP2RY12 | |
| SCHEMBL12920233 | 0.79 | ADORA1 (0.35) | ADORA3ADORA1ADORA2AP2RY12DOT1L | |
| SCHEMBL16244658 | 0.77 | SLC29A1 (0.52) | ADORA3ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884885-B2 | Synthesis of labile base protected-modified deoxy and modified ribo nucleosides, corresponding phosphoramidites and supports and their use in high purity oligonucleotide synthesis | CHEMGENES CORPORATION (US) | 2018-02-06 | — | — | US | disclosed |