Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25820294 | 1.00 | TDP1 (0.40) | TDP1CYP3A4 | |
| SCHEMBL8738746 | 0.88 | TDP1 (0.45) | TDP1 | |
| SCHEMBL13381787 | 0.83 | TDP1 (0.43) | TDP1CYP3A4 | |
| SCHEMBL10099855 | 0.83 | TDP1 (0.43) | TDP1CYP3A4 | |
| SCHEMBL21767819 | 0.80 | TDP1 (0.42) | TDP1 | |
| SCHEMBL3915321 | 0.78 | TDP1 (0.66) | TDP1 | |
| SCHEMBL29560022 | 0.78 | TDP1 (0.46) | TDP1CYP3A4 | |
| SCHEMBL12143969 | 0.78 | TDP1 (0.39) | TDP1 | |
| SCHEMBL3910888 | 0.76 | TDP1 (0.68) | TDP1 | |
| SCHEMBL9349437 | 0.76 | CYP3A4 (0.43) | TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884118-B2 | Multicomponent degradable cationic polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-02-06 | — | — | US | disclosed |