Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13381787 | 0.95 | TDP1 (0.43) | TDP1 | |
| SCHEMBL10099855 | 0.95 | TDP1 (0.43) | TDP1 | |
| SCHEMBL25820294 | 0.88 | TDP1 (0.40) | TDP1 | |
| SCHEMBL19840396 | 0.88 | TDP1 (0.40) | TDP1 | |
| SCHEMBL12119295 | 0.86 | TDP1 (0.41) | TDP1 | |
| SCHEMBL19131302 | 0.86 | TDP1 (0.41) | TDP1 | |
| SCHEMBL2244456 | 0.85 | TDP1 (0.66) | TDP1 | |
| SCHEMBL6747243 | 0.83 | CYP3A4 (0.43) | TDP1 | |
| SCHEMBL9349437 | 0.83 | CYP3A4 (0.43) | TDP1 | |
| SCHEMBL17013553 | 0.80 | TDP1 (0.35) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180177881-A1 | Multicomponent Degradable Cationic Polymers | THE JOHNS HOPKINS UNIVERSITY | 2018-06-28 | — | — | US | disclosed |
| US-9884118-B2 | Multicomponent degradable cationic polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-02-06 | — | — | US | disclosed |
| US-20180028455-A1 | PEPTIDE/PARTICLE DELIVERY SYSTEMS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-02-01 | — | — | US | disclosed |
| US-20170143639-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-05-25 | — | — | US | disclosed |
| US-20150272900-A1 | Layer-By-Layer Approach to Co-Deliver DNA and siRNA via AuNPs: A Potential Platform for Modifying Release Kinetics | THE JOHNS HOPKINS UNIVERSITY | 2015-10-01 | — | — | US | disclosed |
| US-20150273071-A1 | Bioreducible Poly (Beta-Amino Ester)s For siRNA Delivery | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-10-01 | — | — | US | disclosed |
| US-20150250881-A1 | Multicomponent Degradable Cationic Polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-09-10 | — | — | US | disclosed |
| US-8992991-B2 | Multicomponent degradable cationic polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-03-31 | — | — | US | disclosed |
| US-20140294909-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-10-02 | — | — | US | disclosed |
| US-20120128782-A1 | Multicomponent Degradable Cationic Polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150272900-A1 | Layer-By-Layer Approach to Co-Deliver DNA and siRNA via AuNPs: A Potential Platform for Modifying Release Kinetics | DNMT3L, DBNL, HNRNPL | TDP1 275/4885 |
| US-20150250881-A1 | Multicomponent Degradable Cationic Polymers | PEF1, FIBP, PARN | TDP1 296/4885 |
| US-20180177881-A1 | Multicomponent Degradable Cationic Polymers | PEF1, FIBP, PARN | TDP1 296/4885 |
| US-20170143639-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | HNRNPL, HNRNPLL, ACSL3 | TDP1 1281/4885 |
| US-20150273071-A1 | Bioreducible Poly (Beta-Amino Ester)s For siRNA Delivery | AARS1, SLC43A1, PHAX | TDP1 1039/4885 |
| US-20120128782-A1 | Multicomponent Degradable Cationic Polymers | PEF1, FIBP, PARN | TDP1 296/4885 |
| US-20180028455-A1 | PEPTIDE/PARTICLE DELIVERY SYSTEMS | VEGFA, IAPP, FLT1 | TDP1 2541/4885 |
| US-20140294909-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | HNRNPL, HNRNPLL, ACSL3 | TDP1 1281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.