SCHEMBL198407

SCHEMBL198407

CSc1cc(-c2ccccn2)nc(-c2ccccn2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.58
CCR5 P51681 3/20 0.58
CCR8 P51685 3/20 0.58
KDM4E B2RXH2 9/20 0.57
LMNA P02545 4/20 0.57
TP53 P04637 3/20 0.57
ALOX15 P16050 3/20 0.57
L3MBTL1 Q9Y468 3/20 0.57
HTT P42858 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
HSP90AA1 P07900 2/20 0.57
ALPL P05186 1/20 0.57
ALPI P09923 1/20 0.57
ALPG P10696 1/20 0.57
MAPK1 P28482 1/20 0.57
CYP1A2 P05177 1/20 0.54
POLB P06746 1/20 0.54
METAP1 P53582 1/20 0.54
BLM P54132 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9848058 0.92 CCR1 (0.50) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL6702203 0.86 KDM4E (0.60) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL10475780 0.85 GRM5 (0.45) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL11094137 0.85 GRM5 (0.57) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL1366371 0.84 SQOR (0.43) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL13431291 0.84 CCR1 (0.62) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL198135 0.82 GRM5 (0.45) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL23134184 0.80 CCR1 (0.53) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL23134183 0.80 CCR1 (0.53) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL1104803 0.78 CCR1 (0.64) CCR1CCR5CCR8KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210086170-A1 INDIUM GALLIUM NITRIDE NANOSTRUCTURE SYSTEMS AND USES THEREOF SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-03-25 US disclosed
US-9891185-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2018-02-13 US disclosed
US-9662057-B2 Integrated sample acquisition and analyte measurement method ABBOTT DIABETES CARE INC. (US) 2017-05-30 US disclosed
US-20160334356-A1 Small Volume In Vitro Analyte Sensor THERASENSE, INC. 2016-11-17 US disclosed
US-20160235350-A1 Integrated Sample Acquisition and Analyte Measurement Device THERASENSE, INC. 2016-08-18 US disclosed
US-9341591-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-05-17 US disclosed
US-9316609-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-04-19 US disclosed
US-9291592-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-03-22 US disclosed
US-9271669-B2 Method for integrated sample acquisition and analyte measurement device ABBOTT DIABETES CARE INC. (US) 2016-03-01 US disclosed
US-9234863-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-01-12 US disclosed
EP-0187984-A1 Polymeric mordant containing nitrogen-coordinating ligand for metallizable dyes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-07-23 EP disclosed
EP-0187340-A1 Photographic products employing novel nondiffusible metal complexes of AZO dyes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-07-16 EP disclosed
EP-0186868-A2 Photographic element and process for providing metal complex color images EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-07-09 EP disclosed
US-4599389-A COLOR PHOTOGRAPHY DIFFUSION TRANSFER EASTMAN KODAK COMPANY (US) 1986-07-08 US disclosed
US-4598030-A Photographic products employing novel nondiffusible metal complexes of azo dyes EASTMAN KODAK COMPANY (US) 1986-07-01 US disclosed
US-4581314-A FOR COLOR DIFFUSION TRANSFER PHOTOGRAPHY; RAPID DYE METALLIZATION EASTMAN KODAK COMPANY (US) 1986-04-08 US disclosed
US-4562139-A STABILITY; DIFFUSIBILITY; COLOR FILMS; SELF-DEVELOPMENT EASTMAN KODAK COMPANY (US) 1985-12-31 US disclosed
US-4555478-A Photographic element and process for providing metal complex color images EASTMAN KODAK COMPANY (US) 1985-11-26 US disclosed
US-4555477-A Photographic element and process utilizing metal complex color masking dyes EASTMAN KODAK COMPANY (US) 1985-11-26 US disclosed
US-4451659-A Method of making known and previously unavailable pyrylium salts RENSSELAER POLYTECHNIC INSTITUTE (US) 1984-05-29 US disclosed