Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19840693 | 0.86 | EPHX1 (0.38) | EPHX1 | |
| SCHEMBL25788853 | 0.82 | EPHX1 (0.33) | EPHX1 | |
| SCHEMBL15029007 | 0.74 | EPHX2 (0.45) | EPHX1EPHX2 | |
| SCHEMBL22744566 | 0.73 | GRIN2D (0.37) | — | |
| SCHEMBL18844882 | 0.70 | ALDH1A1 (0.40) | EPHX2 | |
| SCHEMBL21360943 | 0.69 | GRIN2D (0.34) | — | |
| SCHEMBL25856177 | 0.68 | PTPN11 (0.40) | PTPN11 | |
| SCHEMBL19365947 | 0.67 | GRIN2D (0.42) | — | |
| SCHEMBL23509274 | 0.66 | PTPN11 (0.39) | PTPN11 | |
| SCHEMBL31485054 | 0.65 | JAK2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884832-B2 | Inhibitors targeting drug-resistant influenza A | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-02-06 | — | — | US | disclosed |