Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19841003 | 0.92 | SMN1; SMN2 (0.44) | MEN1KMT2ATDP1SMN1; SMN2MAOA | |
| SCHEMBL19840880 | 0.88 | EPHX2 (0.47) | MEN1KMT2ASMN1; SMN2DRD4KDM4E | |
| SCHEMBL19840865 | 0.88 | BCHE (0.55) | MEN1KMT2A | |
| SCHEMBL19840887 | 0.87 | CHRM2 (0.46) | MEN1KMT2ASMN1; SMN2CHRM2HDAC3 | |
| SCHEMBL19840713 | 0.87 | CYP1A2 (0.49) | — | |
| SCHEMBL19841116 | 0.85 | MEN1 (0.41) | MEN1KMT2AGAAMAPTL3MBTL1 | |
| SCHEMBL19840866 | 0.85 | ANPEP (0.35) | SMN1; SMN2CHRM2L3MBTL1 | |
| SCHEMBL19840869 | 0.85 | ANPEP (0.35) | SMN1; SMN2CHRM2L3MBTL1 | |
| SCHEMBL19841127 | 0.85 | ALDH1A1 (0.40) | SMN1; SMN2GAAMAPTKDM4E | |
| SCHEMBL19840793 | 0.84 | CYP1A2 (0.34) | SMN1; SMN2CHRM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884832-B2 | Inhibitors targeting drug-resistant influenza A | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-02-06 | — | — | US | disclosed |