Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16665640 | 0.89 | FASN (0.43) | EPHX1FASNMTNR1AMTNR1BCXCR2 | |
| SCHEMBL14818633 | 0.86 | EPHX1 (0.40) | EPHX1FASNATMMTNR1AMTNR1B | |
| SCHEMBL8275256 | 0.84 | ATM (0.48) | EPHX1ATMKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL15199663 | 0.82 | FASN (0.36) | EPHX1FASNATMMTNR1AMTNR1B | |
| SCHEMBL25146775 | 0.81 | FASN (0.38) | EPHX1FASNATMKDM4EBTK | |
| SCHEMBL20696999 | 0.81 | FASN (0.38) | EPHX1FASNATMKDM4EBTK | |
| SCHEMBL20696900 | 0.81 | FASN (0.38) | EPHX1FASNATMKDM4EBTK | |
| SCHEMBL21238476 | 0.81 | FASN (0.38) | EPHX1FASNATMKDM4EBTK | |
| SCHEMBL20987777 | 0.81 | ALDH1A1 (0.49) | CA12CA9FASNATMKDM4E | |
| SCHEMBL13457789 | 0.81 | FASN (0.38) | EPHX1FASNATMKDM4EBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884851-B2 | Heterocycle-bisamide inhibitors of scavenger receptor BI | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-02-06 | — | — | US | disclosed |