Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28518676 | 0.91 | MAPK14 (0.41) | MAPK14MAPK13MAPK12MAPK11PDK2 | |
| SCHEMBL20181951 | 0.91 | PDK2 (0.44) | MAPK14MAPK13MAPK12MAPK11PDK2 | |
| SCHEMBL24794045 | 0.88 | PDK2 (0.36) | MAPK14MAPK13MAPK12MAPK11PDK2 | |
| SCHEMBL17858151 | 0.87 | RAB9A (0.43) | PDK2LMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL782290 | 0.85 | PDK2 (0.51) | MAPK14PDK2ALDH1A1HPGDMAPT | |
| SCHEMBL12950969 | 0.85 | PDK2 (0.51) | MAPK14PDK2ALDH1A1HPGDMAPT | |
| SCHEMBL29462256 | 0.85 | PDK2 (0.51) | MAPK14PDK2ALDH1A1HPGDMAPT | |
| SCHEMBL17883239 | 0.85 | PDK2 (0.43) | PDK2LMNAALDH1A1HPGDPLA2G7 | |
| SCHEMBL14681457 | 0.85 | PDK2 (0.40) | MAPK14MAPK13MAPK12MAPK11PDK2 | |
| SCHEMBL29950946 | 0.85 | PDK2 (0.43) | PDK2LMNAALDH1A1HPGDPLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112430191-A | Pyrene compound containing aromatic amine substitution | 北京夏禾科技有限公司 | 2021-03-02 | — | — | CN | disclosed |
| US-10249831-B2 | Electronic device containing cyclic lactams | MERCK PATENT GMBH (DE) | 2019-04-02 | — | — | US | disclosed |
| US-20180040832-A1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | MERCK PATENT GMBH (DE) | 2018-02-08 | — | — | US | disclosed |
| US-20180040832-A1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | MERCK PATENT GMBH (DE) | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10249831-B2 | Electronic device containing cyclic lactams | OXA1L, UROD, MRPL21 | MAPK14 4232/4885MAPK13 4783/4885MAPK12 3911/4885 |
| US-20180040832-A1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | OXA1L, UROD, MRPL21 | MAPK14 4232/4885MAPK13 4783/4885MAPK12 3911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.