Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 10/20 | 0.64 |
| ▸ | GABRD | O14764 | 10/20 | 0.64 |
| ▸ | GABRA1 | P14867 | 10/20 | 0.64 |
| ▸ | GABRB1 | P18505 | 10/20 | 0.64 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.64 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.64 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.64 |
| ▸ | GABRA3 | P34903 | 10/20 | 0.64 |
| ▸ | GABRA2 | P47869 | 10/20 | 0.64 |
| ▸ | GABRB2 | P47870 | 10/20 | 0.64 |
| ▸ | GABRA4 | P48169 | 10/20 | 0.64 |
| ▸ | GABRE | P78334 | 10/20 | 0.64 |
| ▸ | GABRA6 | Q16445 | 10/20 | 0.64 |
| ▸ | GABRG1 | Q8N1C3 | 10/20 | 0.64 |
| ▸ | GABRG3 | Q99928 | 10/20 | 0.64 |
| ▸ | GABRQ | Q9UN88 | 10/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | AHR | P35869 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28526733 | 0.86 | GABRP (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL23803036 | 0.85 | AHR (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL406255 | 0.81 | CHUK (0.62) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL12938276 | 0.81 | GABRP (0.68) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6446989 | 0.78 | GABRP (0.64) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10644440 | 0.78 | GABRP (0.64) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3333771 | 0.78 | GABRP (0.64) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28643704 | 0.78 | GABRP (0.64) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10642293 | 0.78 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1982871 | 0.78 | GABRP (0.64) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4731358-A | β-carbolines and their use as tranquilizers | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-03-15 | — | — | US | claimed |
| CN-114605313-B | Bicarbazole material based on fluorene units and preparation method and application thereof | 南京邮电大学 | 2023-07-21 | — | — | CN | disclosed |
| WO-2011070298-A1 | DI-SUBSTITUTED 9H-PYRIDO[3,4-B]INDOLE DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2011-06-16 | — | — | WO | disclosed |
| WO-2011070298-A1 | DI-SUBSTITUTED 9H-PYRIDO[3,4-B]INDOLE DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2011-06-16 | — | — | WO | disclosed |
| US-4731358-A | β-carbolines and their use as tranquilizers | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-03-15 | — | — | US | disclosed |