Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR2 | Q16832 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28357397 | 0.98 | DDR2 (0.62) | DDR2KMT2AKDM4EMEN1CYP3A4 | |
| SCHEMBL18079061 | 0.84 | KMT2A (0.59) | DDR2KMT2AKDM4EMEN1CYP3A4 | |
| SCHEMBL19846946 | 0.84 | KMT2A (0.64) | DDR2KMT2AKDM4EMEN1CYP3A4 | |
| SCHEMBL31319016 | 0.84 | ABCG2 (0.60) | DDR2KMT2AKDM4EMEN1CYP3A4 | |
| SCHEMBL5178618 | 0.84 | ABCG2 (0.60) | DDR2KMT2AKDM4EMEN1CYP3A4 | |
| SCHEMBL29169913 | 0.81 | KMT2A (0.60) | DDR2KMT2AKDM4EMEN1CYP3A4 | |
| SCHEMBL30699386 | 0.81 | KDM4E (0.62) | DDR2KMT2AKDM4EMEN1CYP3A4 | |
| SCHEMBL9019380 | 0.81 | DDR2 (0.60) | DDR2KMT2AKDM4EMEN1CYP3A4 | |
| SCHEMBL21318410 | 0.81 | DDR2 (0.56) | DDR2KMT2AKDM4EMEN1CYP3A4 | |
| SCHEMBL30672824 | 0.80 | KMT2A (0.55) | DDR2KMT2AKDM4EMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3266774-B1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AS PHOSPHATIDYLINOSITOL 3-KINASE DELTA INHIBITOR AND USE THEREOF | NANJING SANHOME PHARMACEUTICAL CO LTD (CN) | 2019-09-04 | — | — | EP | disclosed |
| US-20180037576-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AS PHOSPHATIDYLINOSITOL 3-KINASE DELTA INHIBITOR AND USE THEREOF | NANJING SANHOME PHARMACEUTICAL CO., LTD. (CN) | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037576-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AS PHOSPHATIDYLINOSITOL 3-KINASE DELTA INHIBITOR AND USE THEREOF | PIK3CA, PIK3CD, PIK3CB | DDR2 3289/4885KMT2A 3628/4885KDM4E 2353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.