Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR2 | Q16832 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30672824 | 0.87 | KMT2A (0.55) | DDR2KMT2AKDM4EMEN1CYP3A4 | |
| SCHEMBL8630309 | 0.84 | KMT2A (0.52) | DDR2KMT2AKDM4EMEN1CYP3A4 | |
| SCHEMBL31511844 | 0.83 | KMT2A (0.51) | DDR2KMT2AKDM4EMEN1CYP3A4 | |
| SCHEMBL623887 | 0.83 | VKORC1 (0.59) | DDR2KMT2AKDM4EMEN1CYP3A4 | |
| SCHEMBL19846946 | 0.81 | KMT2A (0.64) | DDR2KMT2AKDM4EMEN1CYP3A4 | |
| SCHEMBL19846957 | 0.81 | DDR2 (0.64) | DDR2KMT2AKDM4EMEN1CYP3A4 | |
| SCHEMBL5178618 | 0.81 | ABCG2 (0.60) | DDR2KMT2AKDM4EMEN1CYP3A4 | |
| SCHEMBL18079061 | 0.81 | KMT2A (0.59) | DDR2KMT2AKDM4EMEN1CYP3A4 | |
| SCHEMBL31319016 | 0.81 | ABCG2 (0.60) | DDR2KMT2AKDM4EMEN1CYP3A4 | |
| Hydrochloric Acid SCHEMBL28357397 | 0.80 | DDR2 (0.62) | DDR2KMT2AKDM4EMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450588-B1 | Substituted 3-thia- or 3-oxa-alkyl flavones, process for their preparation, their application and drugs based on these compounds as well as intermediates | HOECHST AG (DE) | 1996-02-28 | — | — | EP | claimed |
| EP-0450588-A1 | Substituted 3-thia- or 3-oxa-alkyl flavones, process for their preparation, their application and drugs based on these compounds as well as intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-09 | — | — | EP | claimed |
| EP-0450588-B1 | Substituted 3-thia- or 3-oxa-alkyl flavones, process for their preparation, their application and drugs based on these compounds as well as intermediates | HOECHST AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0450588-A1 | Substituted 3-thia- or 3-oxa-alkyl flavones, process for their preparation, their application and drugs based on these compounds as well as intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-09 | — | — | EP | disclosed |
| EP-0450588-A1 | Substituted 3-thia- or 3-oxa-alkyl flavones, process for their preparation, their application and drugs based on these compounds as well as intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-09 | — | — | EP | disclosed |