Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 15/20 | 0.67 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | HTR1D | P28221 | 3/20 | 0.43 |
| ▸ | HTR1B | P28222 | 3/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19834079 | 0.93 | MGLL (0.57) | MGLLGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL19833803 | 0.92 | MGLL (0.79) | MGLLHTR1AHTR1DHTR1B | |
| SCHEMBL19833732 | 0.89 | MGLL (0.63) | MGLLHTR1AHTR1DHTR1BADRB1 | |
| SCHEMBL19833920 | 0.89 | MGLL (0.68) | MGLLHTR1AHTR1DHTR1BADRB1 | |
| SCHEMBL19834013 | 0.89 | MGLL (0.68) | MGLLHTR1AHTR1DHTR1BADRB1 | |
| SCHEMBL19833785 | 0.89 | MGLL (0.65) | MGLLHTR1AHTR1DHTR1BADRB1 | |
| SCHEMBL19834150 | 0.88 | MGLL (0.78) | MGLLHTR1AHTR1DHTR1BALDH1A1 | |
| SCHEMBL19833871 | 0.87 | MGLL (0.79) | MGLLHTR1AHTR1DHTR1B | |
| SCHEMBL19833983 | 0.87 | MGLL (0.81) | MGLLGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL19971776 | 0.86 | MGLL (0.58) | MGLLHTR1AHTR1DHTR1BADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3279191-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-02-07 | — | — | EP | disclosed |