Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.75 |
| ▸ | HTR1D | P28221 | 3/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | HTR1B | P28222 | 1/20 | 0.55 |
| ▸ | NR3C2 | P08235 | 10/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19834166 | 0.93 | MGLL (0.77) | MGLLHTR1DHTR1AHTR1BNR3C2 | |
| SCHEMBL19834016 | 0.92 | MGLL (0.78) | MGLLHTR1DHTR1AHTR1BNR3C2 | |
| SCHEMBL19833997 | 0.86 | MGLL (0.70) | MGLLHTR1DHTR1AHTR1BNR3C2 | |
| SCHEMBL19833736 | 0.86 | MGLL (0.89) | MGLLHTR1DHTR1AHTR1BNR3C2 | |
| SCHEMBL19833739 | 0.86 | MGLL (0.82) | MGLLHTR1DHTR1AHTR1BNR3C2 | |
| SCHEMBL19833728 | 0.86 | MGLL (0.72) | MGLLHTR1DHTR1AHTR1BNR3C2 | |
| SCHEMBL19833955 | 0.85 | MGLL (0.71) | MGLLHTR1DHTR1AHTR1BNR3C2 | |
| SCHEMBL19834081 | 0.85 | MGLL (1.00) | MGLLHTR1DHTR1AHTR1BNR3C2 | |
| SCHEMBL19833760 | 0.85 | MGLL (0.71) | MGLLHTR1DHTR1AHTR1BNR3C2 | |
| SCHEMBL19833813 | 0.84 | MGLL (0.70) | MGLLHTR1DHTR1AHTR1BNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3279191-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2020-09-02 | — | — | EP | disclosed |
| EP-3279191-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-02-07 | — | — | EP | disclosed |