SCHEMBL19848484

SCHEMBL19848484

N#Cc1ccc2nnn(-c3ccccc3)c2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.49
NPC1 O15118 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
ALDH1A1 P00352 5/20 0.46
MAPT P10636 4/20 0.45
GAA P10253 2/20 0.45
HPGD P15428 2/20 0.45
CCR6 P51684 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
NT5E P21589 4/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
KMT2A Q03164 1/20 0.42
IDO1 P14902 1/20 0.42
TDO2 P48775 1/20 0.42
POLB P06746 1/20 0.41
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.40
ACSS2 Q9NR19 1/20 0.40
GLA P06280 1/20 0.39
TDP2 O95551 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13610401 0.88 KDM4E (0.60) KDM4ENPC1L3MBTL1ALDH1A1MAPT
SCHEMBL19848488 0.86 ALDH1A1 (0.42) KDM4ENPC1L3MBTL1ALDH1A1MAPT
SCHEMBL19848735 0.76 NPC1 (0.53) KDM4ENPC1L3MBTL1ALDH1A1MAPT
SCHEMBL28668108 0.76 NPC1 (0.53) KDM4ENPC1L3MBTL1ALDH1A1GAA
SCHEMBL19848719 0.76 KDM4E (0.53) KDM4ENPC1L3MBTL1ALDH1A1MAPT
SCHEMBL11545910 0.76 NPC1 (0.53) KDM4ENPC1L3MBTL1ALDH1A1MAPT
SCHEMBL8605903 0.76 NPC1 (0.76) KDM4ENPC1L3MBTL1ALDH1A1MAPT
SCHEMBL30543440 0.76 NPC1 (0.53) KDM4ENPC1L3MBTL1ALDH1A1GAA
SCHEMBL19848485 0.75 GRM2 (0.60) KDM4ENPC1ALDH1A1MAPTKMT2A
SCHEMBL165333 0.74 SMN1; SMN2 (0.71) KDM4ENPC1L3MBTL1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10756394-B2 Nonaqueous electrolyte and nonaqueous secondary battery ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-08-25 US disclosed
EP-3467930-A1 NONAQUEOUS ELECTROLYTE AND NONAQUEOUS SECONDARY BATTERY ASAHI KASEI KABUSHIKI KAISHA (JP) 2019-04-10 EP disclosed
US-20180062213-A1 Nonaqueous Electrolyte and Nonaqueous Secondary Battery ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-03-01 US disclosed
EP-3279997-A1 NONAQUEOUS ELECTROLYTE AND NONAQUEOUS SECONDARY BATTERY Asahi Kasei Kabushiki Kaisha (JP) 2018-02-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10756394-B2 Nonaqueous electrolyte and nonaqueous secondary battery BPTF, BRD4, KCNN2 KDM4E 2256/4885NPC1 2529/4885L3MBTL1 2127/4885
US-20180062213-A1 Nonaqueous Electrolyte and Nonaqueous Secondary Battery BPTF, BRD4, KCNN2 KDM4E 2256/4885NPC1 2529/4885L3MBTL1 2127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.