⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22790615 | 0.81 | — | — | |
| SCHEMBL15726863 | 0.79 | — | — | |
| SCHEMBL14788414 | 0.77 | ADRB2 (0.34) | — | |
| SCHEMBL19851143 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL16825035 | 0.77 | KDM4E (0.30) | — | |
| SCHEMBL13967232 | 0.75 | KDM4E (0.37) | — | |
| SCHEMBL4346271 | 0.75 | CYP2C19 (0.36) | — | |
| SCHEMBL14791589 | 0.75 | TP53 (0.32) | — | |
| SCHEMBL17830452 | 0.73 | TSHR (0.31) | — | |
| SCHEMBL5270837 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3494120-B1 | OXADIAZOLOPYRIDINE DERIVATIVES FOR USE AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2021-03-17 | — | — | EP | disclosed |
| WO-2018024653-A1 | OXADIAZOLOPYRIDINE DERIVATES FOR USE AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-02-08 | — | — | WO | disclosed |