Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL1985189

CCCCCC(O)CCO.OCCOCCO

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
HTT P42858 2/20 0.55
MEN1 O00255 1/20 0.55
THRB P10828 1/20 0.55
KMT2A Q03164 1/20 0.55
MAPT P10636 1/20 0.55
FFAR4 Q5NUL3 1/20 0.44
USP2 O75604 1/20 0.44
FFAR1 O14842 1/20 0.44
PSMD14 O00487 2/20 0.43
PLA2G1B P04054 2/20 0.43
MMP2 P08253 2/20 0.43
ATG4B Q9Y4P1 2/20 0.43
HSP90AA1 P07900 1/20 0.43
RAD52 P43351 1/20 0.43
NFKB1 P19838 1/20 0.43
GPR84 Q9NQS5 5/20 0.42
MAPK1 P28482 1/20 0.40
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12459736 0.87 FFAR4 (0.54) TSHRMEN1THRBKMT2AFFAR4
SCHEMBL5414027 0.87 FFAR4 (0.54) TSHRMEN1THRBKMT2AFFAR4
SCHEMBL304078 0.87 FFAR4 (0.54) TSHRMEN1THRBKMT2AFFAR4
Di(Hydroxyethyl)Ether SCHEMBL28181733 0.86 HTT (0.59) TSHRHTTMEN1THRBKMT2A
SCHEMBL15007062 0.86 TSHR (0.58) TSHRHTTMEN1THRBKMT2A
SCHEMBL15007008 0.86 TSHR (0.46) TSHRHTTMEN1THRBKMT2A
Diethylene Glycol Monoethyl Ether SCHEMBL5010022 0.85 MEN1 (0.58) TSHRHTTMEN1THRBKMT2A
SCHEMBL23188459 0.85 FFAR4 (0.57) TSHRHTTMEN1KMT2AMAPT
SCHEMBL995404 0.85 FFAR4 (0.57) TSHRHTTMEN1KMT2AMAPT
SCHEMBL7209288 0.85 FFAR4 (0.57) TSHRHTTMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2339659-B1 CHARGE-TRANSPORTING VARNISHES NISSAN CHEMICAL IND LTD (JP) 2016-02-10 EP disclosed
US-8747700-B2 Charge-transporting varnishes NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-06-10 US disclosed
US-20110195355-A1 CHARGE-TRANSPORTING VARNISHES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2011-08-11 US disclosed
EP-2339659-A1 CHARGE-TRANSPORTING VARNISHES Nissan Chemical Industries, Ltd. (JP) 2011-06-29 EP disclosed